9 documents found, page 1 of 1
Cold atmospheric plasma activation of human gingival fibroblasts for improved w...
Silva, Neusa; Marques, Joana; Brito da Cruz, Mariana; Luis, Henrique; Mata, António; Sério, SusanaSoft tissue regeneration plays a crucial role after oral surgery, as the successful healing of the soft tissue is a primary indicator of an efficacious intervention. Cold atmospheric plasma (CAP) has recently emerged as a promising therapeutic modality, exhibiting notable effects on cell migration and proliferation. Despite its potential, the dental application of CAP remains underexplored. This in vitro study ...
Hyaluronic acid-based gels for oral application: comparison of in vitro effects...
Marques, Ana Filipa Silva; Silva, Neusa; Brito da Cruz, Mariana; Marques, Joana; Mata, AntónioPurpose: This study aimed to evaluate the cytotoxic effects of different topical hyaluronic acid-based gels on human gingival fibroblasts and oral bacteria. Methods: Four different hyaluronate gels - Bexident® Aftas (BA), GUM® AftaClear (AfC), Gengigel®(G), Aloclair® Plus (AlC) and a chlorhexidine gel - Bexident®Gums(BG) were selected. Human gingival fibroblasts (HGF) were seeded in 48-well plates with differen...
Bio-piezoelectric ceramic composites for electroactive implants—biological perf...
Fernandes, Beatriz Ferreira; Silva, Neusa; Marques, Joana Faria; Da Cruz, Mariana Brito; Tiainen, Laura Katariina; Gasik, MichaelBarium titanate (BaTiO<sub>3</sub>) piezoelectric ceramic may be a potential alternative for promoting osseointegration due to its piezoelectric properties similar to bone electric potentials generated in loading function. In this sense, the aim of this in vitro study was to evaluate the cellular response of human osteoblasts and gingival fibroblasts as well as the impact on <i>S. oralis</i> when in contact wit...
The applications of cold atmospheric plasma in dentistry
Silva, Neusa; Marques, Joana; da Cruz, Mariana B.; Luis, Henrique; Sério, Susana; Mata, AntónioCold atmospheric plasma (CAP), as a noninvasive technology, has shown promise in dentistry as it might successfully treat various oral conditions. The antimicrobial capacity of CAP has been proven and it is effective in reducing the main microorganisms responsible for oral infections. Furthermore, CAP has also been explored in the field of tissue regeneration with a great response from both soft and hard tissue...
Human gingival fibroblast and osteoblast behavior on groove-milled zirconia imp...
Cruz, Mariana Brito da; Marques, Joana Faria; Silva, Neusa; Madeira, Sara Cristina Soares; Carvalho, Óscar Samuel Novais; Silva, Filipe SamuelTwo type of cells representing periodontal hard tissues (osteoblasts) and soft tissues (fibroblasts) were evaluated in response to microgroove-milled zirconia surfaces. A total of 90 zirconia discs were randomly assigned to four width-standardized milling microgroove-textured groups and a control group without grooves (UT). The sandblast and acid-etch protocol were applied to all samples. Both cell lines were c...
Biomimetic implant surfaces and their role in biological integration—a concise ...
Cruz, Mariana Brito; Silva, Neusa; Marques, Joana Faria; Mata, António; Silva, Filipe Samuel; Caramês, JoãoBackground: The increased use of dental implants in oral rehabilitation has been followed by the development of new biomaterials as well as improvements in the performance of biomaterials already in use. This triggers the need for appropriate analytical approaches to assess the biological and, ultimately, clinical benefits of these approaches. Aims: To address the role of physical, chemical, mechanical, and bio...
Human gingival fibroblast and osteoblast behavior on groove-milled zirconia imp...
Brito da Cruz, Mariana; Marques, Joana; Silva, Neusa; Madeira, Sara; Carvalho, Óscar; Silva, Filipe Samuel; Caramês, João; Mata, AntónioTwo type of cells representing periodontal hard tissues (osteoblasts) and soft tissues (fibroblasts) were evaluated in response to microgroove-milled zirconia surfaces. A total of 90 zirconia discs were randomly assigned to four width-standardized milling microgroove-textured groups and a control group without grooves (UT). The sandblast and acid-etch protocol were applied to all samples. Both cell lines were c...
Biomimetic implant surfaces and their role in biological integration: a concise...
Brito da Cruz, Mariana; Silva, Neusa; Marques, Joana; Mata, António; Silva, Felipe Samuel; Caramês, JoãoBackground: The increased use of dental implants in oral rehabilitation has been followed by the development of new biomaterials as well as improvements in the performance of biomaterials already in use. This triggers the need for appropriate analytical approaches to assess the biological and, ultimately, clinical benefits of these approaches. Aims: To address the role of physical, chemical, mechanical, and bio...
Propriedades antioxidantes de extractos metanólicos de Lactarius deliciosus (L....
Ferreira, Isabel C.F.R.; Baptista, Paula; Vilas-Boas, Miguel; Azevedo, Cristina; Silva, Neusa; Barroso, Patrícia; Freire, Joana C.F.As espec1es reactivas de oxigénio formam-se durante o metabolismo celular normal. mas em altas concentrações podem tornar-se tóxicas. As células dos mamíferos possuem defesas intracelulares como a superóxido dismutase, a catalase ou a glutationa peroxidase, que as protegem de níveis excessivos de radicais livres. A adição de compostos exógenos, nomeadamente vitaminas (A, E, β-caroteno), minerais ( selénio, zinc...