111 documents found, page 1 of 12

Evaluation of P-glycoprotein activity mediated by fiscalin derivatives at the r...

Background: P-glycoprotein (P-gp) is an active efflux pump that reduces xenobiotics’ accumulation inside cells, and which activity can be modulated by inhibitors, inducers and activators [1,2]. The first ones have been used to counteract the multidrug resistance (MDR) phenomena and the inducers and activators have been proposed as a therapeutic approach in intoxication scenarios. In fact, P-gp binds several unr...

Carpal Tunnel Release with Regional Block of the Wrist: An Effective Anesthesia

Introduction: Carpal tunnel syndrome is the most common form of nerve compression, and its treatment is almost always surgical with the release of the median nerve. However, there is still no consensus on the type of anesthesia used for this procedure. This study aimed to evaluate whether wrist block represents a valid alternative to local anesthesia. Methods: To that end, 40 patients indicated for surgical rel...

The use of manipulative materials for the development of number sense and calcu...

This study aimed to understand the impact of using manipulatives on the development of number sense and mental calculation in first-grade students. Conducted within an action-research framework, the study involved a class of 18 students over three weeks. The intervention consisted of a sequence of tasks using the ten-frame, bead string, and dot cards, promoting representation, decomposition, and problem-solving...

Exploring Different Configurations of Health Determinants in European Countries

Financial literacy bias: a comparison between students and nonstudents

Purpose – This work uses survey data from the Portuguese Securities Market Commission (Comissão de Mercado de Valores Mobiliários – CMVM) to examine financial literacy and literacy bias. The main objective of this study is to shed light on this issue by identifying the individual characteristics that are associated with financial literacy, namely overconfidence and underconfidence, which in turn might help expl...

Effects of warm-up duration on acute physical performance in highly trained mal...

Warm-up is a traditional pre-match routine that aims to enhance players’ readiness to subsequent activity. Manipulating the warm-up structure may be important to enhance acute performance. This study aimed to investigate the effects of different warm-up dura- tions on futsal players’ physical performance. Twelve highly trained male futsal players participated in this study during the in-season. All players perf...

Revealing the essential and sufficient conditions for the energy consumption di...

Assessing Energy Performance Certificates for Buildings: A Fuzzy Set Qualitativ...

This article presents causal recipes leading to high and low energy consumption efficiency performances using fuzzy set Qualitative Comparative Analysis (fsQCA). The study found that several causal conditions are sufficient for high energy efficiency performance, including several fiscal and financial incentive policies, a highly educated population, many completed dwellings, and low GDP. The study also found t...

AN APPROACH TO AREA MAGNITUDE IN THE POST-PANDEMIC 2ND GRADE

In this article, we present an investigation about the Geometry and Measurement domain, in the 2nd grade, inherent to the content "Areas", based on the manipulation of concrete materials, like the geoboard and the pattern blocks, and technological tools, like the geoboard and the pattern shapes. This study was based on a didactic sequence, with five working sessions, and sought to answer two problem questions: ...

CONNECTIONS AND APPLICATIONS OF MATHEMATICS IN A STEAM EDUCATION CURRICULAR UNIT

Mathematics is a fundamental component of STEAM education, providing a foundation for many scientific and technological fields. It provides a foundation for scientific inquiry, technological development, engineering, and the arts. By emphasizing the connections between mathematics and other STEAM areas, we can help students develop a deeper understanding of the world and the necessary skills for success in the ...