13 documents found, page 1 of 2
Multifunctional hybrid structures made of open-cell aluminum foam impregnated w...
Pinto, Susana C.; Silva, Nuno H. C. S.; Pinto, Ricardo J. B.; Freire, Carmen S. R.; Duarte, Isabel; Vicente, Romeu; Vesenjak, MatejThis work focuses on exploring combinations of disintegrated bacterial cellulose nanofibres (BC) with graphene oxide (GO) (reduced and non-reduced) and phase change materials (PCMs) prepared in the form of foam-like structures. The presence of GO remarkable improves the fire-retardancy and provides dimensional stability to the foams while PCMs gives thermal energy storage capacity. The foams were exposed to met...
Extraction of high value triterpenic acids from eucalyptus globulus biomass usi...
Silva, Nuno H. C. S.; Morais, Eduarda S.; Carmen S. R. Freire; Freire, Mara G.; Silvestre, Armando J. D.Triterpenic acids (TTAs), known for their promising biological properties, can be found in different biomass sources and related by-products, such as Eucalyptus globulus bark, and have been extracted using organic volatile solvents such as dichloromethane. Recently, deep eutectic solvents (DES) have been identified as promising alternatives for the extraction of value-added compounds from biomass. In the presen...
Anti-inflammatory and antioxidant nanostructured cellulose membranes loaded wit...
Morais, Eduarda S.; Silva, Nuno H. C. S.; Sintra, Tânia E.; Santos, Sónia A. O.; Neves, Bruno Miguel; Almeida, Isabel F.; Costa, Paulo C.The utilization of natural compounds, such as phenolic acids and biopolymers, in the healthcare domain is gaining increasing attention. In this study, bacterial nanocellulose (BC) membranes were loaded with ionic liquids (ILs) based on phenolic acids. These ionic compounds, with improved solubility and bioavailability, were prepared by combining the cholinium cation with anions derived from caffeic, ellagic and...
Tuning lysozyme nanofibers dimensions using deep eutectic solvents for improved...
Silva, Nuno H. C. S.; Vilela, Carla; Pinto, Ricardo J. B.; Martins, Manuel A.; Marrucho, Isabel M.; Freire, Carmen S. R.Deep eutectic solvents (DESs), a novel generation of solvents, have recently been described as efficient and timesaving fibrillation agents for proteins. In this context, the present work aims at assessing the effect of the hydrogen bond donor (HBD) of cholinium chloride ([Ch]Cl):carboxylic acid based DESs on the dimensions (length and width) of lysozyme nanofibers (LNFs). Mono-, di- and tri-carboxylic acids (a...
Production of lysozyme nanofibers using deep eutectic solvent aqueous solutions
Silva, Nuno H. C. S.; Pinto, Ricardo J. B.; Freire, Carmen S. R.; Marrucho, Isabel M.Amyloid fibrils have recently gained a lot of attention due to their morphology, functionality and mechanical strength, allowing for their application in nanofiber-based materials, biosensors, bioactive membranes and tissue engineering scaffolds. The in vitro production of amyloid fibrils is still a slow process, thus hampering the massive production of nanofibers and its consequent use. This work presents a ne...
Bioactive transparent films based on polysaccharides and cholinium carboxylate ...
Tome, Liliana C.; Silva, Nuno H. C. S.; Soares, Hugo R.; Coroadinha, Ana S.; Sadocco, Patrizia; Marrucho, Isabel M.; Freire, Carmen S. R.Novel antibacterial and biocompatible transparent films based on chitosan or pullulan and two bioactive ionic liquids (ILs), cholinium hexanoate and cholinium citrate, were prepared. These ILs were selected based on their MIC values against several microbial strains, film-forming ability when blended with the polysaccharides and biocompatibility against designated human cell lines. The films were obtained throu...
Antimicrobial bacterial cellulose nanocomposites prepared by in situ polymeriza...
Figueiredo, Ana R. P.; Figueiredo, Andrea G. P. R.; Silva, Nuno H. C. S.; Barros-Timmons, Ana; Almeida, Adelaide; Silvestre, Armando J. D.tAntimicrobial bacterial cellulose/poly(2-aminoethyl methacrylate) (BC/PAEM) nanocomposites wereprepared by in situ radical polymerization of 2-aminoethyl methacrylate, using variable amounts of N,N-methylenebis(acrylamide) (MBA) as cross-linker. The obtained nanocomposites were characterized interms of their structure, morphology, thermal stability, mechanical properties and antibacterial activ-ity. The ensuin...
Antimicrobial bacterial cellulose nanocomposites prepared by in situ polymeriza...
Figueiredo, Ana R. P.; Figueiredo, Andrea G. P. R.; Silva, Nuno H. C. S.; Barros-Timmons, Ana; Almeida, Adelaide; Silvestre, Armando J. D.Antimicrobial bacterial cellulose/poly(2-aminoethyl methacrylate) (BC/PAEM) nanocomposites were prepared by in situ radical polymerization of 2-aminoethyl methacrylate, using variable amounts of N,N-methylenebis(acrylamide) (MBA) as cross-linker. The obtained nanocomposites were characterized in terms of their structure, morphology, thermal stability, mechanical properties and antibacterial activity. The ensuin...
Bacterial cellulose membranes as transdermal delivery systems for diclofenac: I...
Silva, Nuno H. C. S.; Rodrigues, Artur Filipe; Almeida, Isabel F.; Costa, Paulo C.; Rosado, Catarina; Pascoal Neto, Carlos; Silvestre, Armando J. D.Bacterial cellulose (BC) membranes were explored as novel nanostructured transdermal delivery systems for diclofenac sodium salt (a typical non-steroidal anti-inflammatory drug). Diclofenac sodium salt loaded BC membranes were prepared through a simple methodology, using glycerol as plasticizer, and characterized in terms of structure, morphology and swelling behavior. The membranes were very homogeneous, quite...
Protein-based materials: from sources to innovative sustainable materials for b...
Silva, Nuno H. C. S.; Vilela, Carla; Marrucho, Isabel M.; Freire, Carmen S. R.; Neto, Carlos Pascoal; Silvestre, Armando J. D.Proteins display an essential role in numerous natural systems due to their structural and biological properties. Given their unique properties, proteins have been thoroughly investigated in the last few decades, offering a myriad of solutions for the development of innovative biomaterials, including films, foams, composites and gels, in particular for biomedical applications such as drug delivery systems, bios...