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Production, extraction and characterization of natural fungal pigments from Pen...

Fonseca, C.; Silva, Nuno R.; Silvério, Sara Isabel Cruz; Teixeira, J. A.

Natural pigments can be used for different purposes, namely in the textile industry for dyeing cloths, or in the food industry, as colouring agents. Nowadays, some food grade pigments produced by filamentous fungi, namely Monascus pigments, Arpink red TM from Penicillium oxalicum, riboflavin from Ashbya gossypii, as well as lycopene and β-carotene from Blakeslea trispora can be found in the market. In the Europ...


Interrelationship between partition behavior of organic compounds and proteins ...

Ferreira, Luisa A.; Silva, Nuno R.; Wlodarczyk, Samarina R.; Loureiro, Joana A.; Madeira, Pedro P.; Teixeira, J. A.; Uversky, Vladimir N.

Partition behavior of adenosine and guanine mononucleotides was examined in aqueous dextran-polyethylene glycol (PEG) and PEG-sodium sulfate two-phase systems. The partition coefficients for each series of mononucleotides were analyzed as a functions of the number of phosphate groups and found to be dependent on the nature of nucleic base and on the type of \ATPS\ utilized. It was concluded that an average cont...


Origin of salt additive effect on solute partitioning in aqueous polyethylene g...

Silva, Nuno R.; Ferreira, Luísa A.; Mikheeva, Larissa M.; Teixeira, J. A.; Zaslavsky, Boris Y.

Partitioning of a homologous series of dinitrophenylted (DNP-) amino acids with aliphatic side chains was examined in aqueous polyethylene glycol (PEG)-8000–sodium sulfate two-phase systems (ATPS) with the additives NaSCN, NaClO4, and NaH2PO4 at concentrations varied from 0.025 M up to 0.54 M. The differences between the relative hydrophobicities and electrostatic properties of the two phases in all ATPS were e...


Automation in anesthesia: computer controlled propofol infusion and data acquis...

Bressan, Nadja; Castro, Ana; Braga, Carlos; Lages, Jose; Silva, Nuno R.; Portela, Paulo; Miranda, Pedro; Oliveira, Sergio; Mendes, Joaquim

This work presents the improvement of a software for a clinical setup, the Anesthesia Synchronization Software (ASYS). The first version presented the data acquisition from cerebral monitors and a partial control with Target Controlled Infusion (TCI) system. Based on pharmacokinetic models, the effect-site and plasma concentrations can be related with the drug dose infused and vice versa. This later version com...


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