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Diagnosis and Laboratory Follow-Up of Patients with Multiple Myeloma: Guideline...
Pires, Ana Marta; Barreto, João Pedro; Caetano, Joana; Soares, Maria José; Geraldes, Catarina; Fernandes, Bruno; Coucelo, Margarida; Chacim, SérgioMultiple myeloma is a neoplasm of plasma cells that in most cases is associated with the secretion of monoclonal immunoglobulins and can involve multiple organs. Its timely diagnosis is essential to limit or avoid irreversible damage and dysfunction of target organs. Appropriate initial stratification of patients allows for optimization in the selection and sequence of therapy, as well as proper follow-up durin...
Diagnosis and laboratory follow-up of patients with multiple myeloma: guideline...
Pires, Ana Marta; Barreto, João Pedro; Caetano, Joana; Soares, Maria José; Geraldes, Catarina; Fernandes, Bruno; Coucelo, Margarida; Chacim, SérgioMultiple myeloma is a neoplasm of plasma cells that in most cases is associated with the secretion of monoclonal immunoglobulins and can involve multiple organs. Its timely diagnosis is essential to limit or avoid irreversible damage and dysfunction of target organs. Appropriate initial stratification of patients allows for optimization in the selection and sequence of therapy, as well as proper follow-up durin...
Young Adults with Cancer in Portugal: a survey by the Young Adult Study Group w...
Almeida, Marta; Coelho, Andreia; Ferreira, Ana; Silva, Ant´ónio; Macedo, Daniela; Vasques, Hugo; Chacim, Sérgio; Noronha, Cátia; Brito, MargaridaYoung adults with cancer (YAC) pose a challenge due to their unique characteristics that require specialized care. An ESMO -SIOPE survey revealed that in Europe, there is suboptimal and uneven provision of care for YAC, highlighting the need to assess their status in the Portuguese healthcare system. The Portuguese Group of YAC developed a questionnaire to assess the needs of physicians and available resources ...
Chimeric Antigen Receptor T‐Cell Therapy: Potentially Nephrotoxic?
Alferes, Daniela; Coelho, Inês; Ferreira, Hugo; Chuva, Teresa; Paiva, Ana; Chacim, Sérgio; Mariz, José Mário; Maximino Costa, JoséIntroduction: Chimeric antigen receptor (CAR) T‐cell therapy is an effective new treatment for hematologic malignan‐ cies. In this study, we aimed to characterize the acute kidney injury (AKI) and electrolyte disorders among adults with refractory and relapsed haematological malignancies treated with CAR‐T therapy and explore clinical outcomes. Methods: A retrospective, observational study was performed. Adult ...
Practical Considerations for the Daratumumab Management in Portuguese Routine C...
Geraldes, Catarina; Neves, Manuel; Chacim, Sérgio; da Costa, Fernando LealThe recent therapeutic progress in multiple myeloma (MM) has led to the introduction of novel and highly potent drug classes. Daratumumab was the first CD38-targeting antibody showing to be effective and safe in MM patients as monotherapy and in combination regimens, which led to its rapid implementation in clinical practice. Considering that treatment discontinuation for drug-related adverse events can impact ...
Burnout and occupational stress in the medical residents of oncology, hematolog...
Joaquim, Ana; Custódio, Sandra; Savva-Bordalo, Joana; Chacim, Sérgio; Carvalhais, Inês; Lombo, Liliana; Lopes, Heitor; Araújo, António; Gomes, A. RuiBurnout is a professional syndrome associated with stress caused by overwork. Our aim was to calculate the prevalence of burnout and stress on medical residents of Oncology, Haematology and Radiotherapy in Portugal, as well as to determine predictors of burnout and stress. An anonymous questionnaire was applied (n = 118). Statistical analysis consisted of a descriptive and inferential analysis. The prevalence o...