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Soybean Flour Fortified with Gryllus assimilis Powder to Increase Iron Bioavail...
Barnabé, Michele Lílian da Fonseca; Vicente, Laura Célia de Oliveira Souza; Martins, Karina Vitoria Cipriana; Lacerda, Gabrieli FernandesInsects like Gryllus assimilis have an excellent nutritional profile, including iron. However, the bioavailability of this iron and its effects on intestinal health and oxidative balance remain unclear. To enhance acceptance, insects can be used in powder form and combined with common flours. Objective: This study evaluates the effects of Gryllus assimilis powder, alone or with soy flour, on iron bioavailabilit...
Ointment of Brassica oleracea var. capitata matures the extracellular matrix in...
Sarandy, Mariáurea Matias; Novaes, Rômulo Dias; Matta, Sérgio Luiz Pinto da; Mezencio, Jose Mario da Silveira; Silva, Marcelo Barreto daWound healing is a complex process that aims to restore damaged tissue. Phytotherapeutics, such as cabbage, Brassica oleracea var. capitata (Brassicaceae), and sunflower, Helianthus annuus L. (Asteraceae) oil, are used as wound healers. Five circular wounds, each 12 mm in diameter, were made in the dorsolateral region of each rat. The animals were divided into four groups: balsam (B. oleracea); ointment (B. ole...
Extract of the bark of bathysa cuspidata attenuates the development of chemical...
Rosa, Damiana Diniz; Reis, Sandra Aparecida dos; Siqueira, Nathane Pais; Gonçalves, Reggiani Vilela; Machado, Alessandra Barbosa FerreiraThe aim of this study was to investigate the effect of the bark extract Bathysa cuspidata on chemically induced preneoplastic colorectal lesions in Wistar rats. Forty male rats were randomly divided into four groups (n = 10 each): saline (control group, oral administration of saline solution 0.9%); dimethylsulfoxide (DMSO, vehicle control), B200 (treated with 200 mg/kg bark extract of B. cuspidata), and B400 (t...
Bark extract of Bathysa cuspidata in the treatment of liver injury induced by c...
Gonçalves, Reggiani Vilela; Matta, Sérgio Luis Pinto da; Novaes, Rômulo Dias; Leite, João Paulo Viana; Peluzio, Maria do Carmo GouveiaThe aim of this study was to investigate the effect of bark extract Bathysa cuspidata (BCE) in the reconstitution of hepatic parenchyma and stroma after dysfunction induced by the CCl4. Liver lesions were induced by intraperitoneal administration of CCl4 (1 mL/kg) every 48 h for 12 days. The animals were treated with B. cuspidata extract (BCE) administered by gavage for another 12 days. Forty-nine rats were ran...
Strychnos pseudoquina modulates the morphological reorganization of the scar ti...
Sarandy, Mariáurea Matias; Miranda, Lyvia Lopes; Altoé, Luciana Schulthais; Novaes, Rômulo Dias; Zanuncio, Virgínia Vinha; Leite, João Paulo VianaNatural substances are used in folk medicines to treat injuries. Strychnos pseudoquina has scarring, antipyretic, and antimalarial actions. The present study aimed to analyze the effect of S. pseudoquina on cutaneous wound healing in rats. The S. pseudoquina extract was submitted to phytochemical prospection. The levels of flavonoids and total phenolic compounds in the extract were 50.7 mg/g and 2.59 mg/g, resp...
Exposure to the insecticide endosulfan induces liver morphology alterations and...
Oliveira, Jerusa Maria; Brinati, Alessandro; Miranda, Liany Divina Lima; Morais, Danielle Barbosa; Zanuncio, José Cola; Gonçalves, Reggiani VilelaExposure to pesticides may increase the generation of reactive oxygen species (ROS), leading to oxidation of cell membrane lipids and proteins. Although fruit bats are potentially exposed to pesticides during their entire lifespan, the impacts of this exposure are still poorly investigated. We examined the effects of low, commercially recommended concentrations (0, 1.05 and 2.1 g/l) of an organochlorine insecti...
Influência do laser arseneto de gálio-alumínio em feridas cutâneas de ratos
Gonçalves, Reggiani Vilela; Sousa, Natanael Teixeira Alves de; Silva, Pedro Henrique; Barbosa, Fabiano Sousa; Neves, Clóvis AndradeO presente estudo avaliou o efeito do laser arseneto de gálio-alumínio (GaAsAl) 830nm (30j/cm2) e da pomada Dersani® no processo cicatricial cutâneo de ratos wistar, em relação à proliferação fibroblástica e revascularização. Foram utilizados 18 ratos wistar adultos jovens, machos, com peso médio de 324 g, provenientes do Biotério do Centro de Ciências Biológicas da Universidade Federal de Viçosa. Foram feitas ...
Parasite control and skeletal myositis in Trypanosoma cruzi-infected and exerci...
Novaes, Rômulo Dias; Gonçalves, Reggiani Vilela; Penitente, Arlete Rita; Cupertino, Marli do Carmo; Maldonado, Izabel Regina dos Santos CostaNon-pharmacological strategies have been rarely described in the treatment of infectious diseases.Although exercise training has been recently incorporated in the clinical management of Chagas disease,the rationale basis that supports this indication is poorly understood. Thus, we investigated the effectof an aerobic exercise on the parasitism, inflammation and oxidative tissue damage in a murine modelof Trypan...
Modulation of inflammatory and oxidative status by exercise attenuates cardiac ...
Novaes, Rômulo Dias; Gonçalves, Reggiani Vilela; Penitente, Arlete Rita; Bozi, Luiz Henrique Marchesi; Neves, Clóvis AndradeAims: The rational basis that explains the benefits of exercise therapy on Chagas cardiomyopathy (ChC) is poorly understood. This study investigated the impact of an exercise programon exercise performance, heart parasitism, immunoinflammatory response, fibrogenesis, oxidative damage, and cardiomyocytes contractility in experimental ChC. Main methods: Wistar rats were subjected to a 9-week treadmill running tra...
Influência do laser arseneto de gálio e arseneto de gálio alumínio e pomada cic...
Gonçalves, Reggiani VilelaThe present work had as objective evaluates the healing effect of the gallium aluminum arsenide (GaAsAl) 830nm (30J/cm2) (60J/cm2) laser and gallium arsenide (GaAs) 904nm (4J/cm2) laser, comparing with the Dersani® ointment. The analyzed parameters were the amount of type I and III collagen fibers, and the area of contraction of the wound in the different treatments. They were also analyzed the influence of the...