2 documents found, page 1 of 1
Solid and aqueous magnetic liposomes as nanocarriers for a new potential drug a...
Rodrigues, Ana Rita Oliveira; Silva, Pedro M. L.; Almeida, B. G.; Araújo, João P.; Queiroz, Maria João R. P.; Castanheira, Elisabete M. S.In this work, iron oxide nanoparticles (NPs), with diameters around 12 nm, were synthesized by coprecipitation method. Both aqueous and solid magnetic liposomes containing magnetite NPs were obtained, with sizes below 140 nm. A new antitumor compound, a diarylurea derivative of thienopyridine, active against breast cancer, was incorporated in both aqueous and solid magnetoliposomes, being located mainly in the ...
Solid and aqueous magnetoliposomes as nanocarriers for a new potential drug act...
Rodrigues, Ana Rita Oliveira; Mendes, Pedro M. F.; Silva, Pedro M. L.; Machado, Vera Alexandra Pereira; Almeida, B. G.; Araújo, João P.Iron oxide nanoparticles, with diameters around 12 nm, were synthesized by coprecipitation method. The magnetic properties indicate a superparamagnetic behavior with a coercive field of 9.7 Oe and a blocking temperature of 118 K. Both aqueous and solid magnetoliposomes containing magnetite nanoparticles have sizes below 150 nm, suitable for biomedical applications. Interaction between both types of magnetolipos...