129 documents found, page 1 of 13

Sort by Issue Date

Protocol: Complementarity between informal care and formal care to adults: Know...

Matos, M. O. de.; Bobrowicz-Campos, E.; Silva, R.; Castanheira, F.; Santos, D.

This is the protocol for a Campbell systematic review. The aim of this scoping review is to map, describe and characterize the available evidence on the role that formal care might have in complementing informal caregivers role – romantic partners, parallel family members (e.g., [step]siblings, cousins or in-laws) or descendants (e.g., the care-receivers are [step]parents, [step]aunts/uncles, [step]grandparents...

Date: 2024   |   Origin: Repositório ISCTE

New generation oral appliances for treatment of obstructive sleep apnea

Silva, R.; Pires, L.; Belchior, I.; Moniri, Armin

Oral appliances (OA) have become one of the most important treatments for obstructive sleep apnea (OSA). Efficacy and compliance have been issues raised with this treatment modality. The new generation OAs, using precision technology, are generally smaller devices occupying less space in the mouth. They create less protrusion of the mandible compared to the classical devices. Previous studies on these devices r...


Struggles against financialisation of housing in Lisbon: The case of Habita

Saaristo, S.-M.; Silva, R.

Social movements can seek to challenge the variety of housing financialisation processes in different ways. Focussing on the case of the Habita association, we examine strategies to contest housing financialisation, which has unfolded through different spatiotemporal dynamics fostered by the State, as well as outcomes of this social mobilisation in Portugal. We emphasise the importance of mixing ‘invited’ strat...

Date: 2024   |   Origin: Repositório ISCTE

In silico study of (thio)xanthones-mediated P-glycoprotein activation

Veiga-Matos, J.; dos Santos, D. J. V. A.; Sousa, E.; Prieto Vicente, M.; Remião, F.; Silva, R.

Background: P-glycoprotein (P-gp) is an efflux transporter located at the apical membrane of important barrier tissues, playing a crucial role in the detoxification of endobiotics and xenobiotics [1]. (Thio)xanthonic derivatives have been shown to be able of activating P-gp without increasing its expression, promoting an immediate increase in the amount of transported substrates. Thus, P-gp activation limits th...

Date: 2023   |   Origin: Scientific Letters

Mechanisms behind the neurotoxicity of 2C-I and 25I-NBOMe drugs

Gil-Martins, E.; Cagide, F.; Borer, A.; Barbosa, D. J.; Martins, D.; Fernandes, C.; Remião, F.; Borges, F.; Silva, R.

Background: New Psychoactive Substances (NPS) pose significant health and legal risks worldwide. At the end of 2021, the European Monitoring Centre for Drugs and Drug Addiction was monitoring 886 NPS, 106 of them phenethylamines [1]. Phenethylamine derivatives include 2,5-dimethoxyphenethylamine-based (2C) and N-benzylphenethylamine-based (NBOMe) drugs, widely known for their psychedelic effects. However, their...

Date: 2023   |   Origin: Scientific Letters

Effectiveness of caregiver-provided individual cognitive interventions in older...

Silva, R.; Bobrowicz-Campos, E.; Santos-Costa, P.; Cardoso, R.; Bernardo, J.; Santana, E.; Almeida, I.; Loureiro, R.; Cardoso, D.; Apóstolo, J.

Background: In a society increasingly committed to promoting an active life in the community, new resources are needed to respond to the needs of citizens with Alzheimer’s disease and other forms of dementia. The potential of several individual cognitive interventions to be provided by caregivers has been explored in the literature. Objective: To synthesize the best available evidence on the effectiveness of ca...

Date: 2023   |   Origin: Repositório ISCTE

Individual cognitive stimulation in people with dementia: Good practices

Silva, R.; Santos-Costa, P.; Bobrowicz-Campos, E.; Gil, I.; Cardoso, D.; Apóstolo, J.

Background: Cognitive stimulation (CS) focuses on the intellectual and social stimulation of people with neurocognitive disorders (NCD or dementia). This intervention is widely disseminated in group settings and may not be accessible or adequate to all people with cognitive impairment. Making a Difference 3 (MD3) is an individual CS program in which family (informal) caregivers play the role of home care partne...

Date: 2023   |   Origin: Repositório ISCTE

Antifungal activity of a new derivative of 5-aminoimidazole-4-carbohydrazonamide

Silva, B.; Costa, I.; Silva, R.; Remião, F.; Cerqueira, F.; Ribeiro, Ana Isabel Ferreira; Dantas, Daniela Filipa Costa; Rodrigues, Rui Pedro Vieira

[Excerpt] Fungal infections, as recognized by the World Health Organization (WHO), are among the most worrying challenges for the medical community due to their high incidence, recurrence, and the emergence of resistance to the few available drugs and therapies. The discovery of new molecules with antifungal activity, exhibiting new mechanisms of action and less side effects, thus represents an important step f...


Exploring the direct and indirect effects of innovation on CSR in pharmaceutica...

Zhang, X.; Dias, Á.; Pereira, L.; Silva, R.

Previous studies showed increasing evidence that large firms search for radical innovation as a driver of firm growth, particularly in the research and development sector. Proficiency at innovating via new products remains not merely a key priority for many managers but arguably the ultimate dynamic capability within a firm. However, there is limited understanding of how innovation influences CSR in pharmaceuti...

Date: 2023   |   Origin: Repositório ISCTE

Influência dos rejeitos de uma mina de sulfuretos na qualidade da água de drena...

Araújo, J.; Fonseca, R.; Albuquerque, Maria Teresa; Silva, N.; Silva, R.

The GeoMatRe project aims to find low-cost solutions for water and sediment rehabilitation using raw geomaterials, in abandoned mines of the Iberian Pyritic Belt. One of our case studies is the Caveira mine in southwestern Portugal, where large piles of mining waste, containing significant amounts of metals, record the long history of its exploitation for Au and Ag. After the exhaustion of its reserves, the ext...


129 Results

Queried text

Refine Results

Author





















More optionsLess options

Date





















More optionsLess options

Document Type











More optionsLess options

Funding



Access rights





Resource





















More optionsLess options

Subject





















More optionsLess options