10 documents found, page 1 of 1
Vulvar Tuberculosis-A Rare Manifestation of the Disease
Bragança, C; Gonçalves, I; Guerreiro, L; Janeiro, MTuberculosis is an infectious disease caused by Mycobacterium tuberculosis. According to data from the World Health Organization, this disease remains one of the leading causes of death worldwide. Although it most commonly affects the lungs, tuberculosis can compromise any organ. The present study reports a rare case of vulvar tuberculosis in a postmenopausal woman with a history of asymptomatic pulmonary and p...
Five-membered iminocyclitol a-glucosidase inhibitors: Synthetic,biological scre...
Guerreiro, L; Carreiro, E; Fernandes, L; Cardote, T; Moreira, R; Caldeira, A Teresa; Guedes, R; Burke, A JThe design and synthesis of a small library of pyrrolidine iminocyclitol inhibitors with a structural similarity to 1,4-dideoxy-1,4-imino-D-arabitol (DAB-1) is reported. This library was specifically designed to gain a better insight into the mechanism of inhibition of glycosidases by polyhydroxylated pyrrolidines or iminocyclitols. Pyrrolidine-3,4-diol 15a and pyrrolidine-3,4-diol diacetate 15b had emerged as ...
Mesoporous silica containing sulfonic acid groups as catalysts for alpha-pinene...
Castanheiro, J; Guerreiro, L; Fonseca, I; Ramos, A; Vital, JThe methoxylation of a-pinene was studied over sulfonic acid-functionalized mesoporous silica (MCM-41, PMO) at 60ºC. The support functionalization was achieved by the introduction of 3-(mercaptopropyl)trimethoxysilane onto the surface of these materials either by grafting or by co-condensation. The thiol groups were oxidized to SO3H by treatment with H2O2. All the catalysts were active in the studied reaction b...
Transesterification of soybean oil over sulfonic acid functionalised polymeric ...
Guerreiro, L; Castanheiro, J; Fonseca, I; Martin-Aranda, R; Ramos, A; Vital, JThe transesterification of soybean oil with methanol was studied using as catalyst two Nafion membranes em PVA membranes. The initial activities of the membranes are compared being observed an increase of initial activity with the amount of sulfonic acid groups.
Transesterification of soybean oil over sulfonic acid functionalised
Guerreiro, L; Castanheiro, J; Fonseca, I; Martin-Aranda, R; Ramos, A; Vital, JThe transesterification of soybean oil with methanol was studied using solid acid catalysts, at 60 ºC and atmospheric pressure. Nafion membranes, ion-exchange resins and poly(vinyl alcohol) membranes containing sulfonic groups were used as catalysts for the transesterification reaction studied. The reactions were carried out in a three-necked reactor using all the catalysts in the form of pellets. Nafion and PV...
Esterification of fatty acids to biodiesel over polymers with sulfonic acid groups
Caetano, CS; Guerreiro, L; Fonseca, I; Ramos, A; Vital, J; Castanheiro, JEThe esterification of palmitic acid with methanol was studied using poly(vinyl alcohol) cross-linked with sulfosuccinic acid (SSA) and polystyrene cross-linked with divinylbenzene with sulfonic acid groups, as catalysts, at 60 ºC. It was observed that the PVAmatrixes with sulfonic acid groups were more active than the polystyrene ones. With the most active polymeric matrix (PVA_SSA40), an almost 90% equilibrium...
Estudo comparativo, aleatorizado, em dupla ocultação, de orlistat versus placeb...
Castro, JJ; Dias, T; Chambel, P; Carvalheiro, M; Correia, LG; Guerreiro, L; Marques, O; Medina, JL; Nobre, E; Nunes, JS; Pereira, MC; Polónia, JINTRODUCTION: Obesity is a chronic disease and a serious health problem that leads to increased prevalence of diabetes, hypertension, dyslipidemia and gallbladder disease. OBJECTIVE: To evaluate the efficacy of orlistat for weight loss and improved lipid profile compared to placebo in obese patients with hypercholesterolemia, treated over a period of 6 months. METHODOLOGY: In a 6-month, multicenter (10 centers ...
Estudo Comparativo, Aleatorizado, em Dupla Ocultação, de Orlistat Versus Placeb...
Castro, JJ; Dias, T; Chambel, P; Carvalheiro, M; Correia, LG; Guerreiro, L; Marques, O; Medina, JL; Nobre, E; Silva Nunes, J; Pereira, MC; Polónia, JINTRODUCTION: Obesity is a chronic disease and a serious health problem that leads to increased prevalence of diabetes, hypertension, dyslipidemia and gallbladder disease. OBJECTIVE: To evaluate the efficacy of orlistat for weight loss and improved lipid profile compared to placebo in obese patients with hypercholesterolemia, treated over a period of 6 months. METHODOLOGY: In a 6-month, multicenter (10 centers ...
The endocrine pancreas.
Cortesão, L; Saraiva, A M; Guerreiro, LThe islets of Langerhans provide energy storage and disposal, and protection from plasma glucose excursions, especially hypoglycemia. Insulin-dependent diabetes mellitus (IDDM) results from autoimmune beta-cell damage. Prevention of IDDM has already been achieved in animal investigation and some centers are now screening and treating individuals at high risk for developing IDDM. Immunosuppressive drugs can indu...
Pure autonomic failure.
Ducla-Soares, J L; Guerreiro, A S; Póvoa, P; Alvares, E; Guerreiro, L; Carrilho, F; Santos, M; Figueirinhas, J; Carvalho, MWe present the case of a 64-year-old woman who, in the past 5 years, complained of constipation/diarrhea, hyposudoresis, xerostomia and xerophthalmia, dysuria and orthostatic hypotension. Cardiovascular reflexes analysis revealed sympathetic and parasympathetic failure. Norepinephrine was markedly reduced, both lying and after tilt. Norepinephrine infusion determined a significant rise in blood pressure, allowi...