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NADES-in-Oil Emulsions Enriched with Essential Oils for Cosmetic Application

Freitas, David; Rocha, Diana; Santos, Joana; Noro, Jennifer Martins; Tavares, Tânia D.; Teixeira, Marta O.; Araújo, Daniela; Castro, Joana Isabel Reis

This research aims to explore the potential benefits of natural deep eutectic solvents (NADES) in formulating translucent NADES-in-oil emulsions (TEs) containing essential oils (EOs) for cosmetic applications. The TEs investigated in this study are based on previous formulations, consisting of 50 wt.% egg phosphatidylcholine (EPC), 20 wt.% ethanol, 20 wt.% olive oil (OlO), thyme oil (TO), or oregano oil (OrO), ...


Control of Stemphylium vesicarium in "Rocha" pear using encapsulated essential ...

Mendonça, Inês; Fernandes, Beatriz; Almeida, Carina Manuela Fernandes; Serrano, Carmo; Leão, Miguel; Venâncio, Armando; Silva, Sónia Carina

[Excerpt] Introduction Stemphylium vesicarium is a plant-pathogenic fungus that poses a significant challenge to pear production, where it causes brown spot of pear (BSP) [1]. The "Rocha" pear, an exclusively Portuguese variety of high importance has been experiencing substantial losses due to BSP [2]. The rise of fungicide resistance and concerns about their environmental impact have driven the search for sust...


Advances in whole genome sequencing for foodborne pathogens: implications for c...

Gomes, Emílio; Araújo, Daniela; Nogueira, Teresa; Oliveira, Ricardo; Silva, Sónia Carina; Oliveira, Lorena V. N.; Azevedo, Nuno F.; Almeida, Carina

Foodborne outbreaks affecting millions of people worldwide are a significant and growing global health threat, exacerbated by the emergence of new and increasingly virulent foodborne pathogens. Traditional methods of detecting these outbreaks, including culture-based techniques, serotyping and molecular methods such as real-time PCR, are still widely used. However, these approaches often lack the precision and ...


Swine industry: validated PCR-based method for detecting enterotoxigenic Escher...

Barros, Margarida; Castro, Joana Isabel Reis; Oliveira, Ricardo; Campos, Ana Maria; Araújo, Daniela; Silva, Sónia Carina; Almeida, Gonçalo Nieto

[Excerpt] Enterotoxigenic E. coli (ETEC) infections lead to significant costs for the swine industry worldwide. Bacterial fimbriae (F4/F5/F6/F18/F41) allow the adhesion of the bacteria to epithelial cells, and when both the immunological systems and the gut mic ro biota are poorly developed, ETEC colonizes and produces one or more enterotoxins (LT/ STa/ STb) that can have local and systemic effects. Therefore, ...


Towards a machine learning framework for predicting MicroRNAs involved in Candi...

Miranda, Tiago; Ferraz, Filipa; Henriques, Mariana; Silva, Sónia Carina; Gonçalves, Bruna Fernandes

Infections caused by Candida species present significant clinical challenges, leading to high morbidity and mortality rates. Emerging research suggests that microRNAs (miRNAs) may serve as valuable biomarkers for diagnosing and treating candidiasis, although the field is still developing. The scarcity of reported miRNAs associated with candidiasis stems from the complexities and costs of screening numerous pote...


Students' summer internships in a research centre: the impact on scientific lit...

Saraiva, Elisa; Silva, Sónia Carina; Castro, Joana Isabel Reis; Araújo, Daniela; Almeida, Carina Manuela Fernandes; Azevedo, Maria Manuel

Science communication is crucial for engaging society in real-life contexts. In this line of thought, research centres play a pivotal role in promoting dynamic and interactive communication that enables science to be disseminated. This study constitutes a qualitative research based on a case study involving middle school students, researchers and teachers, which took place in a research centre in Portugal that ...


Application of antisense therapy to control Nakaseomyces glabratus infections

Serra, Patrícia; Gonçalves, Bruna; Henriques, Mariana; Castro, Joana; Araújo, Daniela; Silva, Sónia Carina

Canclicla infections affect billions of people worlclwicle, with high morbidity ancl mortality rates (40-60CX,) [l] ancl require long hospital stays ancl increase healthcare costs, which places a significant socio-economic burclen on the economy [2]. Canclicla glabrata (now reclassified as Nakaseomyces glabratus) poses a significant clinical challenge, clue to its increasing levels of resistance to conventional...


Impact of thermal treatment on Talaromyces trachyspermus spores inactivation

Sousa, Diana F.; Noronha, L.; Venâncio, Armando; Silva, Sónia Carina

[Excerpt] Introduction Heat-resistant molds (HRM) pose a significant challenge to the fruit juice industry, as they can endure heat treatment and cause product spoilage.[...]


Killer yeasts as sustainable solutions for foodborne pathogens control

Serra, Patrícia; Araújo, Daniela Eira; Gomes, Fernanda Isabel Antunes; Almeida Aguiar, Cristina; Silva, Sónia Carina

[Excerpt] lntroduction Killer yeasts produce toxins that inhibit other microorganisms, providing a competitive advantage in a wide range of environments, from natural ecosystems to industrial applications. Their potential as natural biocontrol agents has been explored, particularly in food systems, where the control of spoilage organisms and foodborne pathogens is essential to guarantee safety and quality.[...]


Comprehensive molecular characterization of anti-EFG1 2'OMe effects on C. albic...

Silva, Diana; Silva, Sónia Carina; Henriques, Mariana; Araújo, Daniela; Gonçalves, Bruna Fernandes

Candidiasis is a fungal infection primarily caused by Candida albicans. It affects millions of people worldwide and poses significant clinical challenges, resulting in high morbidity and mortality rates, largely due to increasing resistance to conventional antifungal therapies resulting from their widespread use [1]. Innovative therapies, such as antisense oligonucleotides (ASOs), are being explored to address ...


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