Objectives Although axial spondyloarthritis (axSpA) typically begins before age 45, late-onset axSpA (lo-axSpA) has been widely recognized. While existing literature describes this subgroup, data on therapeutic approaches remain limited. Therefore, we aimed to evaluate the efficacy and safety of biologic DMARDs in patients with lo-axSpA.Methods We conducted a retrospective, multicentre, national cohort study us...
The addition of cork to a natural rubber compound and the vulcanization parameters were studied in terms of their influence on the properties of cork–rubber materials. The characterization of different compounds was carried out and included in the determination of mechanical properties related to the application of cork–rubber composites as vibration isolation pads, such as static and dynamic behavior under com...
Os Hidrocarbonetos Aromáticos Policíclicos (HAPs) são contaminantes persistentes em meio aquoso. Estes compostos são conhecidos pelas suas propriedades carcinogénicas, mutagénicas e genotóxicas. O principal objetivo deste trabalho consistiu na avaliação das potencialidades de subprodutos da indústria corticeira, como adsorventes alternativos para a remoção de cinco HAPs em meio aquoso: benzo(a)pireno, benzo(ghi...
Actualmente, os métodos mais eficazes de remoção de cianotoxinas envolvem o uso de tecnologias dispendiosas. Os carvões activados são ainda de elevado custo pelo que a procura de adsorventes alternativos é o foco de estudos de tratamento de águas destinadas ao consumo humano. O presente trabalho tem como objectivo a avaliação do potencial de utilização de granulados de cortiça para a remoção de MCLR. Para isso,...
Cyanotoxins and mainly microcystin-LR (MCLR) is a potent and ubiquitous freshwater toxin that poses a risk for human and animal health. According to the Guidelines for Drinking Water Quality published by WHO in 2011, the maximum concentration of MCLR allowed in water for human consumption is 1 g.L-1. The methods currently used to achieve effective MCLR removal are highly costly and so, the search for new, cost...
Industrial pre-treated cork - granules of expanded corkboard, prepared from renewable biomass - was used for the first time as precursor for the preparation of eco-friendly activated carbons by chemical (K2CO3 and KOH) and physical (steam) activation. Samples with different textural (microporosity/micro + mesoporosity) and surface chemistry (acidic/basic) were obtained. In the best compromise between porosity d...
The technical feasibility of using stopper-derived cork as an effective biosorbent towards bivalent mercury at environmentally relevant concentrations and conditions was evaluated in this study. Only 25 mg/L of cork powder was able to achieve 94 % of mercury removal for an initial mercury concentration of 500 mu g/L. It was found that under the conditions tested, the efficiency of mercury removal expressed as e...