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Enzyme-responsive vitamin D-based micelles for paclitaxel-controlled delivery a...
Peixoto, Diana; Ravasco, João M. J. M.; Blanco Fernandez, Barbara; Veiga, Francisco; Concheiro, Angel; Conde, João; Paiva-Santos, Ana CláudiaPublisher Copyright: © 2025 The Authors; Pancreatic ductal adenocarcinoma (PDAC) remains one of the most feared diseases worldwide owing to its poor prognosis, negligible therapeutic advances, and high mortality. Herein, multifunctional enzyme-responsive micelles for the controlled delivery of paclitaxel (PTX) were prepared to circumvent its current clinical challenges. Accordingly, two enzyme-responsive struct...
Exosome membrane-coated nanosystems
Shao, Minmin; Lopes, Daniela; Lopes, Joana; Yousefiasl, Satar; Macário-Soares, Ana; Peixoto, Diana; Ferreira-Faria, Inês; Veiga, Francisco; Conde, JoãoThe authors acknowledge the financial support from the grants 2021.05914.BD (given to D.P.) and PTDC/BTM-MAT/4738/2020 project (given to A.C.P.-S., J.C., and F.V.) from Fundacão para a Ciência e Tecnologia (FCT). J.C. acknowledges the European Research Council Starting Grant (ERC-StG-2019-848325).; Bio-mimicking principles have recently been proposed for the surface functionalization of nanoparticles (NPs). Suc...
Bioengineered exosomal-membrane-camouflaged abiotic nanocarriers
Lopes, Daniela; Lopes, Joana; Pereira-Silva, Miguel; Peixoto, Diana; Rabiee, Navid; Veiga, Francisco; Moradi, Omid; Guo, Zhan Hu; Wang, Xiang DongFunding This work was supported by grants from Fundação para a Ciência e Tecnologia (FCT) (SFRH/BD/148771/2019, 2021.05914.BD, PTDC/BTM-MAT/4738/2020), and also from the European Research Council—ERC Starting Grant (848325).; A bio-inspired strategy has recently been developed for camouflaging nanocarriers with biomembranes, such as natural cell membranes or subcellular structure-derived membranes. This strateg...
Macrophage Cell Membrane-Cloaked Nanoplatforms for Biomedical Applications
Lopes, Joana; Lopes, Daniela; Pereira-Silva, Miguel; Peixoto, Diana; Veiga, Francisco; Hamblin, Michael R.; Conde, João; Corbo, ClaudiaFunding: The authors acknowledge the financial support from the grants SFRH/ BD/148771/2019 (given to M.P.-S.) and 2021.05914.BD (given to D.P.), and PTDC/BTM-MAT/4738/2020 project (given to A.C.S. and J.C. (and also F.V., and M.P.-S.)) from Fundação para a Ciência e Tecnologia (FCT). Open access funding provided by Istituto Italiano di Tecnologia within the CRUI-CARE Agreement; Biomimetic approaches utilize na...
Biomimetic cancer cell membrane-coated nanosystems as next-generation cancer th...
Pereira-Silva, Miguel; Santos, Ana Cláudia; Conde, João; Hoskins, Clare; Concheiro, Angel; Alvarez-Lorenzo, Carmen; Veiga, FranciscoFunding This work received financial support from the grant FCT SFRH/BD/148771/ 2019 from Fundação para a Ciência e Tecnologia (FCT).