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Complement Decay-Accelerating Factor is a modulator of influenza A virus lung i...

Santos, NB; Silva, ZEV; Gomes, C; Reis, CA; Amorim, MJ

Clearance of viral infections, such as SARS-CoV-2 and influenza A virus (IAV), must be fine-tuned to eliminate the pathogen without causing immunopathology. As such, an aggressive initial innate immune response favors the host in contrast to a detrimental prolonged inflammation. The complement pathway bridges innate and adaptive immune system and contributes to the response by directly clearing pathogens or inf...

Date: 2021   |   Origin: Repositório Aberto da Universidade do Porto
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