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Synthesis, Antitubercular and Leishmanicidal Evaluation of Resveratrol Analogues

Coimbra,Elaine S.; Santos,Juliana A.; Lima,Larissa L.; Machado,Patrícia A.; Campos,Débora L.; Pavan,Fernando R.; Silva,Adilson D.

In this paper we continue our efforts in the search for new Schiff bases as resveratrol analogues as promising antitubercular and antileishmanial agents. Compounds were evaluated in vitro against Mycobacterium tuberculosis and Leishmania species. Compounds showed varying activity against promastigotes of all Leishmania species tested (concentration leading to reduction of 50% of parasite growth-IC50 values rang...

Date: 2016   |   Origin: Oasisbr

Synthesis of 1,2,3-triazolium-based ionic liquid and preliminary pretreatment t...

Carmo,Arturene M. L.; Stroppa,Pedro H. F.; Corrales,Roberta C. N. R.; Barroso,Anna B. N.; Ferreira-Leitão,Viridiana S.; Silva,Adilson D.

Ionic liquids (ILs) are salts which are liquid at low temperatures, typically with melting points under 100 ºC. In recent years, the properties of many ILs have been extensively studied and have been considered as green solvents capable of replacing traditional organic solvents. Herein, ILs derived from triazole have been synthesized, thus solubility in different solvents increases with the dielectric constant ...

Date: 2014   |   Origin: Oasisbr

Atividades antimicrobiana e leishmanicida das sementes de Pterodon emarginatus ...

Dutra,Rafael C.; Braga,Fernanda G.; Coimbra,Elaine S.; Silva,Adilson D.; Barbosa,Nádia R.

O presente trabalho investigou as atividades antimicrobiana e leishmanicida das sementes de Pterodon emarginatus Vogel. O potencial antimicrobiano do óleo essencial (OE) obtido das sementes foi avaliado através dos testes de difusão em ágar (10, 25 e 50 mg) e determinação da concentração inibitória mínima e utilizou os microorganismos-padrão: Staphylococcus aureus ATCC 25923, Streptococcus mutans ATCC 25175, Ps...

Date: 2009   |   Origin: Oasisbr

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