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Watchful waiting? Portuguese approach to otitis media with effusion

Vera-Cruz, Paulo; Larroudé, António; Gouveia, Nélia; Mendes, Jorge; Coelho, Pedro Simões

Introduction and objective: Otitis media with effusion (OME) is an important public health problem. Several clinical practice guidelines for diagnosis and treatment of OME are in place, including from the American Academy of Otolaryngology-Head and Neck Surgery (AAO-HNS). This study aimed to evaluate the clinical practice of OME diagnosis and treatment among the Otolaryngology medical community working in Portu...


Watchful waiting? Portuguese approach to otitis media with effusion

Vera-Cruz, Paulo; Larroudé, António; Gouveia, Nélia; Mendes, Jorge; Simões-Coelho, Pedro

Introduction and objective: Otitis media with effusion (OME) is an important public health problem. Several clinical practice guidelines for diagnosis and treatment of OME are in place, including from the American Academy of Otolaryngology-Head and Neck Surgery (AAO-HNS). This study aimed to evaluate the clinical practice of OME diagnosis and treatment among the Otolaryngology medical community working in Portu...


Portuguese Authorship in Published Clinical Trials: Differences in Industry and...

Pinheiro Andrade, Maria; Matias, Daniela; Batuca, Joana; Gouveia, Nélia; Mota-Filipe, Hélder; Carreira Monteiro, Emília; Madeira, Catarina

Introduction: The aim of this study was to investigate the Portuguese authorship in publications resulting from trials initiated by the industry or investigators and run in Portugal.Material and Methods: Clinical trials with Portuguese institutions as sponsor or recruiting centers, and registered in four clinical trial registries, in the last 14 years, were assessed. Publications of completed trials, from both ...

Date: 2021   |   Origin: Acta Médica Portuguesa

Eligibility criteria for biologic disease-modifying antirheumatic drugs in axia...

Marona, Jose; Sepriano, Alexandre; Rodrigues-Manica, Santiago; Pimentel-Santos, Fernando; Mourão, Ana Filipa; Gouveia, Nélia; Branco, Jaime Cunha

Objectives To compare definitions of high disease activity of the Ankylosing Spondylitis Disease Activity Score (ASDAS) and Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) in selecting patients for treatment with biologic disease-modifying antirheumatic drugs (bDMARDs). Methods Patients from Rheumatic Diseases Portuguese Register ( R euma. pt) with a clinical diagnosis of axial spondyloarthritis (ax...


Eligibility criteria for biologic disease-modifying antirheumatic drugs in axia...

Marona, José; Sepriano, Alexandre; Rodrigues Manica, Santiago; M. Pimentel-Santos, F.; Mourão, Ana Filipa; Gouveia, Nélia; Branco, Jaime; Santos, Helena

This work was supported by a Research Grant from the InvestigatorInitiated Studies program of Merck Sharp & Dohme (Grant No. 56078). The sponsor did not interfere with the study question, analysis or interpretation of results. AS is supported by a doctoral grant from Fundação para a Ciência e Tecnologia (Foundation for Science and Technology) (SFRH/BD/108246/2015).; OBJECTIVES: To compare definitions of high di...


Effectiveness of switching between TNF inhibitors in patients with axial spondy...

Rodrigues Manica, Santiago; Sepriano, Alexandre; M. Pimentel-Santos, F.; Gouveia, Nélia; Barcelos, Anabela; Branco, Jaime; Bernardes, Miguel

57763]. AS is supported by a doctoral grant from “Fundação para a Ciência e Tecnologia” (SFRH/BD/108246/2015).; Background: To investigate whether the reason to discontinue the first TNF inhibitor (TNFi) affects the response to the second TNFi in axial spondyloarthritis (axSpA). Methods: Patients with axSpA from the Rheumatic Diseases Portuguese Register (ReumaPt), who discontinued their first TNFi and started ...


Eligibility criteria for biologic disease-modifying antirheumatic drugs in axia...

Marona, Jose; Sepriano, Alexandre; Rodrigues-Manica, Santiago; Pimentel-Santos, Fernando; Mourão, Ana Filipa; Gouveia, Nélia; Branco, Jaime Cunha

Objectives: To compare definitions of high disease activity of the Ankylosing Spondylitis Disease Activity Score (ASDAS) and Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) in selecting patients for treatment with biologic disease-modifying antirheumatic drugs (bDMARDs). Methods: Patients from Rheumatic Diseases Portuguese Register (Reuma.pt) with a clinical diagnosis of axial spondyloarthritis (axS...


Effectiveness of switching between TNF inhibitors in patients with axial spondy...

Manica, Santiago Rodrigues; Sepriano, Alexandre; Pimentel-Santos, Fernando; Gouveia, Nélia; Barcelos, Anabela; Branco, Jaime C.; Bernardes, Miguel

Background: To investigate whether the reason to discontinue the first TNF inhibitor (TNFi) affects the response to the second TNFi in axial spondyloarthritis (axSpA). Methods: Patients with axSpA from the Rheumatic Diseases Portuguese Register (ReumaPt), who discontinued their first TNFi and started the second TNFi between June 2008 and May 2018, were included. Response was assessed by the Ankylosing Spondylit...


Performance of referral strategies for spondyloarthritis : a population-based n...

Sepriano, Alexandre Rocha; Ramiro, Sofia; Araújo, Filipe C; Machado, Pedro M; Rodrigues, Ana Maria; Gouveia, Nélia; Eusébio, Mónica; Canhao, Helena

Objectives: To evaluate the performance of the referral strategy (RS) for SpA of a nationwide epidemiological study (EpiReumaPt), as compared with previously proposed RSs. Methods: EpiReumaPt was a three-stage national epidemiologic study. In phase one, 10 661 adult participants were randomly selected and screened for rheumatic and musculoskeletal diseases. In the second phase, positive screenings for ⩾1 rheuma...


Prevalence of rheumatic and musculoskeletal diseases and their impact on health...

Branco, Jaime C.; Rodrigues, Ana M.; Gouveia, Nélia; Eusébio, Mónica; Ramiro, Sofia; Machado, Pedro; da Costa, Leonor Pereira; Mourão, Ana Filipa

Objectives: To estimate the national prevalence of rheumatic and musculoskeletal diseases (RMDs) in the adult Portuguese population and to determine their impact on health-related quality of life (HRQoL), physical function, anxiety and depression. Methods: EpiReumaPt is a national health survey with a three-stage approach. First, 10 661 adult participants were randomly selected. Trained interviewers undertook s...


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