2 documents found, page 1 of 1
Antifungal activity of liriodenine on clinical strains of Cryptococcus neoforma...
Levorato-Vinche,Adriele Dandara; Melhem,Marcia de Souza Carvalho; Bonfietti,Lucas Xavier; de-la-Cruz-Chacón,Iván; Boaro,Carmen Sílvia FernandesAbstract Background: Cryptoccocal meningitis continues to present high incidence among AIDS patients. The treatment of choice is the synergistic combination of flucytosine (5-FC) with amphotericin B deoxycholate (AmBd) or its lipid formulations. However, 5-FC is unavailable in many countries and AmB demands hospitalization. The combination of AmB with the fungistatic fluconazole (FLC) or the use of high FLC dai...
Antifungal activity of liriodenine on agents of systemic mycoses, with emphasis...
Vinche,Adriele Dandara Levorato; de- la-Cruz-Chacón,Iván; González-Esquinca,Alma Rosa; Silva,Julhiany de Fátima da; Ferreira,GiselaAbstract Background: Endemic systemic mycoses remain a health challenge, since these opportunistic diseases are increasingly infecting immunosuppressed patients. The simultaneous use of antifungal compounds and other drugs to treat infectious or non-infectious diseases has led to several interactions and undesirable effects. Thus, new antifungal compounds should be investigated. The present study aimed to evalu...