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Virtual Screening of Secondary Metabolites of the Family Velloziaceae J. Agardh...

Pinheiro,Anderson A. V.; Barros,Renata P. C.; Assis,Edileuza B. de; Maia,Mayara S.; Araújo,Diego I. A. F. de; Sales,Kaio A.; Scotti,Luciana

The objective of this work was to carry out a bibliographic survey of secondary metabolites isolated from the Velloziaceae family, creating a bank of compounds. After the bank was created, four prediction models for potentially active compounds against pathogenic microorganisms (Candida albicans, Escherichia coli, Pseudomonas aeruginosa and Salmonella sp.) were obtained trying to identify which metabolites woul...

Date: 2020   |   Origin: Oasisbr

DOIS NOVOS ALCALOIDES AZAFENANTRENO DE Anaxagorea dolichocarpa Sprague & Sa...

Sales,Kaio A.; Pinheiro,Anderson A. V.; Araújo,Diego I. A. F.; Andrade,Rodrigo S. de; Agra,Maria de Fátima; Sobral,Marianna V.; Magalhães,Hemerson I. F.

A chemical investigation of Anaxagorea dolichocarpa Sprague & Sandwith, a member of Annonaceae family, was carried out. The ethanolic extract from the roots of this plant led, by chromatography tecniches, to isolation of the new azaphenanthrene alkaloids dolichocarpine (1) and 9-methoxyeupolauramine (2), besides the known alkaloids eupolauramine (3), 3-methoxyeupolauridine (4), eupolauramine (5) and 4-methylsam...

Date: 2020   |   Origin: Oasisbr

New neolignans from Krameria tomentosa A. St. -Hil

Madeiro,Sara A. L.; Lucena,Hellane F. S. de; Siqueira,Caroline D.; Duarte,Marcelo C.; Braz-Filho,Raimundo; Barbosa Filho,José M.; Silva,Marcelo S. da

A phytochemical investigation of the roots of Krameria tomentosa A. St. -Hil. led to the isolation of five neolignans, two of them with novel structures [1,1'-(E)-propenyl-4-methoxy3,4'-oxyneolignan (ottomentosa) and 2-(2'-hydroxy-4',6'-dimethoxyphenyl)benzofuran5-carboxylic acid (sobraline)] and three known compounds [eupomatenoid 6, dihydrocarinatidin and 2-(2',4'-dihydroxyphenyl)-5-(E)-propenylbenzofuran]. T...

Date: 2012   |   Origin: Oasisbr

Flavanones from aerial parts of Cordia globosa (Jacq.) Kunth, Boraginaceae

Silva,Sâmia Andricia S. da; Agra,Maria de Fátima; Tavares,Josean F.; da-Cunha,Emídio V. L.; Barbosa-Filho,José Maria; Silva,Marcelo S. da

The phytochemical analysis of aerial parts of Cordia globosa, collected in the Municipality of Picuí, State of Paraíba, Brazil, resulted in the isolation and structural identification of narigenin-4',7-dimethyl ether (0.025 g) and eriodictyol (0.015 g). These compounds are the first flavanones aglycones isolated from the genus Cordia.

Date: 2010   |   Origin: Oasisbr

Natural products with antileprotic activity

Barbosa-Filho,José M.; Nascimento Júnior,Francisco A. do; Tomaz,Anna Cláudia de Andrade; Athayde-Filho,Petrônio F. de; Silva,Marcelo S. da

Leprosy is a chronic infectious disease caused by Mycobacterium leprae bacillus. It was considered to be an incurable disease for ages. Nowadays leprosy is a vanishing disease although we can meet it principally in the tropical zone countries. Brazil has the second greatest number of leprosy cases around the world with almost 30,000 new cases diagnosed in 2005. The present work constitutes a literature review o...

Date: 2007   |   Origin: Oasisbr

O Ácido (8)17,12E,14-labdatrieno-18-óico (labdano302), diterpeno tipo labdano i...

Ribeiro,Luciano A. A.; Tavares,Josean F.; Andrade,Nilza C. de; Silva,Marcelo S. da; Silva,Bagnólia A. da

A espécie Xylopia langsdorffiana St. Hil.. & Tul. é popularmente conhecida como "pimenteira-da-terra" no Sudeste do Brasil. A partir do fracionamento do extrato etanólico, obtido das cascas do caule desta espécie, foi isolado um diterpeno tipo labdano, identificado como sendo o ácido 8(17),12E,14-labdatrieno-18-óico, e que neste trabalho é codificado como labdano302. O labdano302 relaxou o tônus basal dos a...

Date: 2007   |   Origin: Oasisbr

Pimarane Diterpenes and a Sesquiterpene from Salzmmania nitida

Carvalho,Mário G. de; Alves,Josinete S.; da-Cunha,Emidio V. Leitão; Barbosa-Filho,José M.; Silva,Marcelo S. da

Two new terpenoids, (+)-3-oxo-thermarol and 11-acetoxyeudesman-4alpha-methyl-5alpha-ol along with the (+)- thermarol were isolated from the aerial parts of Salzmmania nitida. The structures and unambiguous ¹H and 13C chemical shift assignments were established by spectroscopic means, including homo and heteronuclear techniques.

Date: 2006   |   Origin: Oasisbr

Muscicapines, a new class of guaiane-type sesquiterpene alkaloids from Croton m...

Araújo-Júnior,Vicente T. de; Silva,Marcelo S. da; da-Cunha,Emídio V. Leitão; Agra,Maria de Fátima; Athayde-Filho,Petrônio F. de; Vieira,Ivo J. Curcino

Three new guaiane-type sesquiterpene alkaloids, muscicapine A (1), muscicapine B (2), and muscicapine C (3) were isolated from the roots of Croton muscicapa. The structures were established by analysis of spectroscopic data, mainly 1D and 2D NMR and MS. This is the first report of a new class of guaiane-type sesquiterpene alkaloids.

Date: 2005   |   Origin: Oasisbr

Resposta do coentro à adubação fosfatada em solo com baixo nível de fósforo

Oliveira,Ademar P. de; Araújo,Luciana R. de; Mendes,Jussara Ellen M. F.; Dantas Júnior,Ovídio R.; Silva,Marcelo S. da

O coentro, hortaliça arbustiva anual utilizada em muitos pratos regionais do Norte e Nordeste, é cultivado no estado da Paraíba por pequenos agricultores, sendo verificados baixos rendimentos, devido principalmente à nutrição mineral desequilibrada. O objetivo do trabalho foi avaliar o efeito de doses de P2O5 no rendimento do coentro, cultivar Verdão, em experimento conduzido na Universidade Federal da Paraíba,...

Date: 2004   |   Origin: Oasisbr

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