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Trypanocidal activity of flavonoids and limonoids isolated from Myrsinaceae and...

Leite,Ana C.; Placeres Neto,Artur; Ambrozin,Alessandra R. P.; Fernandes,João B.; Vieira,Paulo C.; Silva,Maria F. das G. F. da; de Albuquerque,Sérgio

The activity of crude extracts of three Rapanea species (Myrsinaceae) and Cipadessa fruticosa (Meliaceae) was evaluated in vitro against the trypomastigote forms of Trypanosoma cruzi. Thirty-three extracts from different organs of these species were assayed and eleven of them showed significant activity (lysis % >50). The fractionation of an active extract from branches of R. lancifolia (99.5%) led to the isola...

Date: 2010 | Origin: Oasisbr

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