3 documents found, page 1 of 1
Clinical Presentation and Treatment of Childhood-Onset Lupus Nephritis
Silva,Rita M.; Correia,Ana L.; Marques,Maria G.; Cordinhã,Carolina; Romãozinho,Catarina; Oliveira,Nuno A.; Carmo,Carmen do; Gomes,Clara; Alves,RuiAbstract Introduction: Lupus nephritis (LN) in childhood usually presents after the age of 10 years and is more common in female children. Despite the availability of effective immunosuppressive therapies, treatment response in childhood‑onset LN remains suboptimal, with 50% to 78% patients in full remission at 24 months. Improvement in survivals have also plateaued in past decades, and up to 9% and 14% of chil...
Early Antibody-Mediated Kidney Transplant Rejection: A Successful Case Without ...
Silva,Rita M.; Leal,Rita; Marques,Maria G.; Rodrigues,Luís; Santos,Lídia; Romãozinho,Catarina; Figueiredo,Arnaldo; Alves,RuiABSTRACT The diagnosis of antibody-mediated rejection has become more common and represents a major cause of kidney graft loss. The ideal treatment remains unknown, with little evidence supporting the use of a specific therapy. The definition of antibody-mediated rejection is based on serologic (presence and/or development of donor-specific antibodies) and histologic (evidence of acute tissue injury with C4d de...
Comparing Kidney Care during the Pandemic in Hospitalized Non-COVID-19 Patients
Silva,Rita M.; Mira,Filipe; Costa,Regina; Reigota,Catarina; Romãozinho,Catarina; Santos,Lèlita; Alves,RuiAbstract Introduction: Coronavirus disease 19 (COVID-19) has caused a direct increase in mortality but not all of it is entirely attributable to COVID-19, meaning there was a higher rate of mortality in non-COVID-19 patients due to the pandemic. The aim of this study was to compare two groups of patients: group 1, which included all of the patients admitted to the Internal Medicine ward during the month of Apri...