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Effect of N-acetylcysteine in hearts of rats submitted to controlled hemorrhagi...

Oliveira Filho,Luiz Dantas de; Saad,Karen Ruggeri; Saad,Paulo Fernandes; Koike,Marcia Kiyomi; Silva,Sônia Maria da; Montero,Edna Frasson de Souza

AbstractIntroduction:Pharmacological therapy is a strategy for the prevention of complications associated with ischemia and reperfusion injury that occurs after volume replacement in the treatment of hemorrhagic shock.Objective:The aim of this study was to evaluate the effect of N-acetylcysteine associated with fluid resuscitation in cardiac injury in a rat hemorrhagic shock model.Methods:Mice Wister male rats ...

Date: 2015   |   Origin: Oasisbr

Study on the vaginal smear of rats submitted to autologous ovarian transplant: ...

Damous,Luciana Lamarão; Silva,Sônia Maria da; Lopes,Renato Antônio Migliano; Sakano,Célia Regina de Souza Bezerra; Simões,Manuel de Jesus

PURPOSE: To evaluate the remote ischemic preconditioning (R-IPC) impact on the quality of the ovarian graft by means of vaginal smear of transplanted rats. METHODS: Sixty rats were used divided in six groups: Control; Fresh transplant (TxF); Cryopreserved transplant (TxC); R-IPC; R-IPC + fresh transplant (TxF+R-IPC); R-IPC + cryopreserved transplant (TxC+R-IPC). R-IPC was performed in the common iliac artery. A...

Date: 2009   |   Origin: Oasisbr

Indirect evaluation of estrogenic activity post heterotopic ovarian autograft i...

Damous,Luciana Lamarão; Silva,Sônia Maria da; Simões,Ricardo dos Santos; Sakano,Célia Regina de Souza Bezerra; Simões,Manuel de Jesus

PURPOSE: To morphologically evaluate the estrogenic effect on the uterus and vagina of rats submitted to ovarian autografts. METHODS: Twenty Wistar EPM-1 adult rats were bilaterally ovariectomized, followed by ovarian transplants in retroperitoneal regions. The animals were divided in four groups of five animals, according to the day of euthanasia: G4, G7, G14 and G21, corresponding to the 4th, 7th, 14th and 21...

Date: 2008   |   Origin: Oasisbr

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