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The impact of atrial voltage and conduction velocity phenotypes on atrial fibri...

Silva Cunha, Pedro; Laranjo, Sérgio; Monteiro, Sofia; Portugal, Guilherme; Guerra, Cátia; Rocha, António Condeixa; Pereira, Mariana; Ferreira, Rui Cruz

Publisher Copyright: 2024 Silva Cunha, Laranjo, Monteiro, Portugal, Guerra, Rocha, Pereira, Ferreira, Heijman and Oliveira.; Introduction: Low atrial voltage and slow conduction velocity (CV) have been associated with atrial fibrillation (AF); however, their interaction and relative importance as early disease markers remain incompletely understood. We aimed to elucidate the relationship between atrial voltage ...


Left Atrial Wall Thickness Estimated by Cardiac CT

Silva Cunha, Pedro; Laranjo, Sérgio; Monteiro, Sofia; Almeida, Inês Grácio; Mendonça, Tiago; Fontes, Iládia; Ferreira, Rui Cruz; Almeida, Ana G

Atrial wall thickness (AWT) is a significant factor in understanding the pathological physiological substrate of atrial fibrillation, with a potentially substantial impact on the outcomes of catheter ablation procedures. Precise measurements of the AWT may provide valuable insights for categorising patients with AF and planning targeted interventions. Objectives: The purpose of this study was to evaluate the ch...


A simplified single transseptal puncture approach using high-density 3D voltage...

Silva Cunha, Pedro; Teixeira, Bárbara Lacerda; Laranjo, Sérgio; Portugal, Guilherme; Valente, Bruno; Delgado, Ana Sofia; Pereira, Mariana

Background: An ablation catheter and a circular mapping catheter requiring a double transeptal puncture (TSP) for left atrial access have been conventionally used for atrial fibrillation (AF) ablation. Recently, different operators have combined a single transseptal puncture technique with 3D high-density mapping catheters for pulmonary vein isolation (PVI). Objective: This study aims to compare two strategies,...


Case report

Silva Cunha, Pedro; Antunes, Diana Oliveira; Laranjo, Sérgio; Coutinho, Ana; Abecasis, João; Oliveira, Mário Martins

Early-onset atrial fibrillation (AF) can be the manifestation of a genetic atrial myopathy. However, specific genetic identification of a mutation causing atrial fibrosis is rare. We report a case of a young patient with an asymptomatic AF, diagnosed during a routine examination. The cardiac MRI revealed extensive atrial fibrosis and the electrophysiology study showed extensive areas of low voltage. The genetic...


The atrial fibrillation burden during the blanking period is predictive of time...

Silva Cunha, Pedro; Portugal, Guilherme; Laranjo, Sérgio; Alves, Marta; Luísa Papoila, Ana; Valente, Bruno; Sofia Delgado, Ana; Lousinha, Ana

Objective: This study aimed to assess whether atrial fibrillation (AF) occurrence or its corresponding daily mean burden (in minutes/day) during the mid to late blanking period after pulmonary vein isolation (PVI), predicts AF recurrence. Methods: Analysis of consecutive first PVI ablation patients undergoing prolonged electrocardiogram (ECG) monitoring during the second and third months after PVI. The clinical...


Sleep apnea and atrial fibrillation - A different kind of rhythm

Sousa, Susana; Silva Cunha, Pedro; Oliveira, Mário M; Drummond, Marta; Bugalho, António


Does permanent atrial fibrillation modify response to cardiac resynchronization...

Abreu, Ana; Oliveira, Mário; Silva Cunha, Pedro; Santa Clara, Helena; Portugal, Guilherme; Gonçalves Rodrigues, Inês; Santos, Vanessa; Morais, Luis

Introduction: The benefits of cardiac resynchronization therapy (CRT) documented in heart failure (HF) may be influenced by atrial fibrillation (AF). We aimed to compare CRT response in patients in AF and in sinus rhythm (SR). Methods: We prospectively studied 101 HF patients treated by CRT. Rates of clinical, echocardiographic and functional response, baseline NYHA class and variation, left ventricular ejectio...


Preditores de resposta à terapêutica de ressincronização cardíaca

Abreu, Ana; Oliveira, Mário; Silva Cunha, Pedro; Santa Clara, Helena; Santos, Vanessa; Portugal, Guilherme; Rio, Pedro; Soares, Rui; Moura Branco, Luísa

Funding: This work was supported by research grant PTDC/DES/120249/2010 from the Foundation for Science and Technology (FCT).; Introduction Cardiac resynchronization therapy (CRT) has modified the prognosis of chronic heart failure (HF) with left ventricular systolic dysfunction. However, 30% of patients do not have a favorable response. The big question is how to determine predictors of response. Aims To ident...


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