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When the shaft breaks: managing a cath lab nightmare

Oliveira, Catarina; Azaredo Raposo, Miguel; Marques da Costa, José; Pinto, Fausto J.; Silva Marques, João

Objective: We describe the case of a 57-year-old male patient with anterior ST-segment elevation myocardial infarction in cardiogenic shock. Coronary angiography revealed severe left main (LM) and triple-vessel disease, and the patient was refused for surgery due to lack of distal grafting landing zone. A shaft fracture occurred during LM percutaneous coronary intervention, leaving the fractured stent hanging i...


Non-invasive derivation of instantaneous free-wave ratio from invasive coronary...

Oliveira, Catarina; Vilela, Marta; Silva Marques, João; Jorge, Claudia; Rodrigues, Tiago; Francisco, Ana Rita; Oliveira, Rita Marante de

Invasive coronary physiology is underused and carries risks/costs. Artificial Intelligence (AI) might enable non-invasive physiology from invasive coronary angiography (CAG), possibly outperforming humans, but has seldom been explored, especially for instantaneous wave-free Ratio (iFR). We aimed to develop binary iFR lesion classification AI models and compare them with human performance. single-center retrospe...


The power of precision medicine: tailoring success in mitral annular calcification

Oliveira, Catarina; Silva Marques, João; Pinto, Fausto J.

An 81-year-old woman with heart failure with normal ejection fraction was diagnosed with mitral annular calcification (MAC) causing moderate–severe mitral disease. Heart team decision was to evaluate candidacy for a valve-in-MAC (ViMAC) procedure due to high anatomic and surgical risk (STS score 12.9%, Euroscore II 5.36%). Pre-procedural CT showed feasibility for ViMAC based on mitral annular area and a MAC sco...


Coronary intravascular lithotripsy effectiveness and safety in a real-world cohort

Oliveira, Catarina; Vilela, Marta; Menezes, Miguel Nobre; Silva Marques, João; Jorge, Claudia; Rodrigues, Tiago; Almeida Duarte, José

Background: Coronary artery calcification is a predictor of adverse outcomes after percutaneous coronary intervention (PCI). Intravascular lithotripsy (IVL) is a promising tool for the treatment of calcified lesions. The aim of this study was to assess the effectiveness and safety of IVL. Methods: A single-center observational study of PCI procedure, with assessment of the outcomes of patients undergoing PCI us...


Three-dimensional simulation for interventional cardiology procedures: face and...

Sequeira, Carolina; Oliveira-Santos, Manuel; Borges Rosa, João; Silva Marques, João; Oliveira Santos, Eduardo; Norte, Gustavo; Gonçalves, Lino

Introduction and objectives: Three-dimensional (3D) model simulation provides the opportunity to manipulate real devices and learn intervention skills in a realistic, controlled, and safe environment. To ensure that simulators provide a realistic surrogate to real procedures they must undergo scientific validation. We aimed to evaluate the 3D-printed simulator SimulHeart® for face and content validity to demons...


The heart in our hands: pathway to a three-dimensional problem solution

Rodrigues, Tiago; Silva Marques, João; Pinto, Fausto J.

Percutaneous closure of paravalvular leaks (PVLs) after aortic valve replacement has emerged as an effective - and often first-line - choice for patients with significant paravalvular regurgitation requiring intervention. The defect can be approached via different routes (antegrade transseptal, retrograde transaortic, or transapical) based on the position of the valve, location of the defect and operator expert...


Late challenges after full plastic jacket in spontaneous coronary dissection

Alves, Patrícia Marques; Santos, Manuel Oliveira; Silva Marques, João; Gonçalves, Lino


The role of natriuretic peptides in defining diagnosis and prognosis of medical...

Silva Marques, João

Natriuretic peptides, BNP and NT-proBNP, are increased in patients who have high myocardial wall tension. They have been extensively used to diagnose heart failure in patients presenting with dyspnoea. BNP and NT-proBNP serum levels are influenced by variables such as age, gender, body mass index and renal function. More recently, their elevation in acute coronary syndromes, stable coronary heart disease, chron...


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