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Integrating Multi-Omics Analysis for Enhanced Diagnosis and Treatment of Gliobl...
Barzegar Behrooz, Amir; Latifi-Navid, Hamid; Silva Rosa, Simone C. da; Swiat, Maciej; Wiechec, Emilia; Vitorino, Carla; Vitorino, Rui; Jamalpoor, ZahraThe most aggressive primary malignant brain tumor in adults is glioblastoma (GBM), which has poor overall survival (OS). There is a high relapse rate among patients with GBM despite maximally safe surgery, radiation therapy, temozolomide (TMZ), and aggressive treatment. Hence, there is an urgent and unmet clinical need for new approaches to managing GBM. The current study identified modules (MYC, EGFR, PIK3CA, ...
Date: 2023
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Origin: Estudo Geral - Universidade de Coimbra