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A Portuguese expert panel position paper on the management of heart failure wit...

Silva-Cardoso, José; Moreira, Emília; Melo, Rachel Tavares de; Moraes-Sarmento, Pedro; Cardim, Nuno; Oliveira, Mário; Gavina, Cristina; Moura, Brenda

In Portugal, a 15.2% prevalence of heart failure with preserved ejection fraction (HFpEF) was recently identified among those aged ≥50 years. HFpEF represents 90% of Portuguese heart failure patients. HFpEF management in Portugal is challenging due to patient heterogeneity, diagnostic and therapeutic complexity, and organizational constraints on the healthcare system. Considering the above, a panel of Portugues...


A Portuguese expert panel position paper on the management of heart failure wit...

Silva-Cardoso, José; Moreira, Emília; Melo, Rachel Tavares de; Moraes-Sarmento, Pedro; Cardim, Nuno; Oliveira, Mário; Gavina, Cristina; Moura, Brenda

Heart failure (HF) with preserved ejection fraction (HFpEF) affects more than 50% of HF patients worldwide, and more than 70% of HF patients aged over 65. This is a complex syndrome with a clinically heterogeneous presentation and a multifactorial pathophysiology, both of which make its diagnosis and treatment challenging. A Portuguese HF expert panel convened to address HFpEF pathophysiology and therapy, as we...


A Portuguese Expert Panel Position Paper on the Management of Heart Failure wit...

Silva-Cardoso, José; Moreira, Emília; Tavares de Melo, Rachel; Moraes-Sarmento, Pedro; Cardim, Nuno; Oliveira, Mário; Gavina, Cristina; Moura, Brenda

In Portugal, a 15.2% prevalence of heart failure with preserved ejection fraction (HFpEF) was recently identified among those aged ≥50 years. HFpEF represents 90% of Portuguese heart failure patients. HFpEF management in Portugal is challenging due to patient heterogeneity, diagnostic and therapeutic complexity, and organizational constraints on the healthcare system. Considering the above, a panel of Portugues...


A Portuguese expert panel position paper on the management of heart failure wit...

Silva-Cardoso, José; Moreira, Emília; Tavares de Melo, Rachel; Moraes-Sarmento, Pedro; Cardim, Nuno; Oliveira, Mario; Gavina, Cristina; Moura, Brenda

Heart failure (HF) with preserved ejection fraction (HFpEF) affects more than 50% of HF patients worldwide, and more than 70% of HF patients aged over 65. This is a complex syndrome with a clinically heterogeneous presentation and a multifactorial pathophysiology, both of which make its diagnosis and treatment challenging. A Portuguese HF expert panel convened to address HFpEF pathophysiology and therapy, as we...


conTemporary reflectiOns regarding heart failure manaGEmenT – How to ovERcome t...

Silva-Cardoso, José; Santos, Jonathan; Araújo, Inês; Andrade, Aurora; Morais Sarmento, Pedro; Santos, Paulo; Moura, Brenda; Marques, Irene

Introduction and objectives: Heart failure (HF) is a complex clinical syndrome that is a significant burden in hospitalisations, morbidity, and mortality. Although a significant effort has been made to better understand its consequences and current barriers in its management, there are still several gaps to address. The present work aimed to identify the views of a multidisciplinary group of health care profess...


Beyond clinical trials: the cost saving associated with Dapagliflozin use in Po...

Brito, Dulce; Fonseca, Cândida; Franco, Fátima; Lopes, Vanessa; Gonçalves, Sara; Baptista, Rui; Sequeira, Joana; Marques, Irene; Rego, Rita

Introduction and objectives: Heart failure (HF) is a clinical syndrome associated with substantial morbidity, mortality, and healthcare costs. Dapagliflozin has proven efficacy in reducing the risk of death and hospitalization in HF patients, regardless of left ventricular ejection fraction (LVEF). This paper aimed to project the potential impact of dapagliflozin on healthcare costs related to HF subsequent hos...


Optimization of heart failure with reduced ejection fraction prognosis-modifyin...

Silva-Cardoso, José; Fonseca, Cândida; Franco, Fátima; Morais, João; Ferreira, Jorge; Brito, Dulce

Heart failure (HF) with reduced ejection fraction (HFrEF) is associated with high rates of hospitalization and death. It also has a negative impact on patients' functional capacity and quality of life, as well as on healthcare costs. In recent years, new HFrEF prognosis-modifying drugs have emerged, leading to intense debate within the international scientific community toward a paradigm shift for the managemen...


SGLT-2 inhibitors: a step forward in the treatment of heart failure with reduce...

Silva-Cardoso, José; Andrade, Aurora; Brito, Dulce; Ferreira, Jorge; Fonseca, Cândida; Peres, Marisa; Franco, Fátima; Moura, Brenda

Heart failure (HF) is a major health problem with a significant impact on morbidity, mortality, quality of life and healthcare costs. Despite the positive impact of disease-modifying therapies developed over the last four decades, HF mortality and hospitalization remain high. We aim at reviewing the evidence supporting the use of sodium-glucose co-transporter-2 (SGLT-2) inhibitors, as a novel strategy for HF wi...


Management of RAASi-associated hyperkalemia in patients with cardiovascular dis...

Silva-Cardoso, José; Brito, Dulce; Frazão, João Miguel; Ferreira, Aníbal; Bettencourt, Paulo; Branco, Patrícia; Fonseca, Cândida

Renin-angiotensin-aldosterone system inhibitors (RAASi) reduce morbidity and mortality in heart failure (HF) with reduced ejection fraction in a dose-dependent manner. They also have a positive impact in other cardiovascular diseases (CVDs). However, RAASi may induce hyperkalemia, a potentially life-threatening disorder. This risk is further increased in those with concomitant chronic kidney disease, diabetes m...


Frequency of sarcopenia in portuguese heart failure outpatients: a cross-sectio...

Valdiviesso, Rui; Santos, Ana Rita Sousa; Moreira, E.; Silva-Cardoso, José; Amaral, Teresa; Borges, Nuno


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