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Non-COVID-19 Respiratory Viral Infection

Nunes-Silva, C; Vilares, AT; Schweitzer, V; Castanhinha, S; Martins, A; Lopes, MJ; Ascoli-Bartoli, T; Canelas, G; Keir, HR; Cunha, F; Silva-Pinto, A

Implemented control measures brought about by the coronavirus disease 2019 (COVID-19) pandemic have changed the prevalence of other respiratory viruses, often relegating them to a secondary plan. However, it must not be forgotten that a diverse group of viruses, including other human coronaviruses, rhinoviruses, respiratory syncytial virus, human metapneumoviruses, parainfluenza and influenza, continue to be re...



Panton-Valentine Leukocidin-Producing Staphylococcus aureus Infection: A Case S...

Prista-Leão, B; Abreu, I; Duro, R; Silva-Pinto, A; Ceia, F; Andrade, P; Sobrinho-Simões, J; Tavares, M; Pereira, JM; Santos, L; Sarmento, A

Panton-Valentine leukocidin-producing Staphylococcus aureus (PVL-SA) is associated with relapsing multifocal skin and soft tissue infections (SSTI), necrotizing pneumonia (NP) and severe musculoskeletal infections. Epidemiology is underknown and underdiagnosis is likely. Recent travel abroad, case clustering and relapsing disease are often reported. We reviewed all cases of PVL-SA infection diagnosed at our cen...


Human Immunodeficiency Virus (HIV) 2 Superinfection in a Patient Receiving Anti...

Ceia, F; Silva-Pinto, A; Carvalho, AC; Piñeiro, C; Soares, J; Serrão, R; Sarmento, A

Dual human immunodeficiency virus (HIV) 1 and HIV-2 superinfections are rare but challenging. A HIV-1–infected patient receiving effective antiretroviral therapy was investigated for a severe CD4+ cell count decline. HIV-2 superinfection was diagnosed and genotypic test revealed mutations conferring resistance to most drug class, limiting options for treatment.


Mycobacterial blood cultures in the diagnosis of tuberculosis in human immunode...

Ceia, F; Santos-Silva, A; Alves, J; Silva-Pinto, A; Oliveira, O; Cláudia Carvalho, A; Ramos, A; Carvalho, T; Sarmento, A; Duarte, R

n/a


Diabetes mellitus in HIV-infected patients: Fasting glucose, A1c, or oral gluco...

Coelho, AR; Moreira, F; Santos, A; Silva-Pinto, A; Sarmento, A; Carvalho, D; Freitas, P

Background: Antiretroviral therapy dramatically reduced HIV-related morbidity and mortality, prolonging the lifespan of HIV-infected patients. Greater duration of infection and exposure to antiretroviral therapy makes these patients susceptible to traditional cardio-metabolic risk factors and pathologies. The optimal diagnostic protocol for Diabetes Mellitus in these patients is still controversial. Haemoglobin...


Visceral adipose tissue and carotid intima-media thickness in HIV-infected pati...

Beires, MT; Silva-Pinto, A; Santos, AC; Madureira, AJ; Pereira, J; Carvalho, D; Sarmento, A; Freitas, P

Background: Combined antiretroviral therapy (cART) in HIV-infected patients has been associated with lipodystrophy, metabolic abnormalities, and an increased risk of cardiovascular disease. Ultrasound measures of carotid artery intima-media thickness (cIMT) have been used as a valid measure of subclinical atherosclerosis and as a tool to predict the risk of cardiovascular events. Our aim was to evaluate the pro...


Imported dengue from 2013 Angola outbreak: Not just serotype 1 was detected

Abreu, C; Silva-Pinto, A; Lazzara, D; Sobrinho-Simões, J; Guimarães, JT; Sarmento, A

BACKGROUND:All the reports from Angola's 2013 dengue outbreak revealed serotype 1. However, previously dengue serotypes 1-4 have been reported in Africa and in 2014 serotype 4 was reported in Angola. OBJECTIVES:To report dengue serotypes in patients returning from Angola during 2013 outbreak. STUDY DESIGN:Retrospective, cross-sectional study. We serotyped the dengue by an in house Polymerase Chain Reaction tech...


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