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Vaccination Recommendations for the Immunocompromised Adult Patient

Abreu, Cândida; Peres, Susana; Cunha, Flávia; Miranda, Joana; Nunes-Silva, Cláudio; Silva-Pinto, André; Ribeiro-Dias, Lúcia; Oliveira, Joaquim

The manuscript collates indications for vaccination in immunocompromised adults based on recommendations from leading international institutions. These individuals have increased vulnerability to vaccine-preventable infectious diseases, and their immune response to vaccination is often weaker than that of immunocompetent individuals. Therefore, whenever possible, it is important to assess vaccine response (sero...

Date: 2025   |   Origin: Acta Médica Portuguesa

Vaccination Recommendations for the Immunocompromised Adult Patient

Abreu, Cândida; Peres, Susana; Cunha, Flávia; Miranda, Joana; Nunes-Silva, Cláudio; Silva-Pinto, André; Ribeiro-Dias, Lúcia; Oliveira, Joaquim

The manuscript collates indications for vaccination in immunocompromised adults based on recommendations from leading international institutions. These individuals have increased vulnerability to vaccine-preventable infectious diseases, and their immune response to vaccination is often weaker than that of immunocompetent individuals. Therefore, whenever possible, it is important to assess vaccine response (sero...


Diagnostic, Therapeutic and Monitoring Approach in Suspected Neurosyphilis: Pro...

Martins, Bárbara; Canelas, Gabriela; Dias, Rafael; Prista-Leão, Beatriz; Silva, Cláudio; Costa, Andreia; Silva-Pinto, André

This clinical guideline was designed to serve as a hospital guide in the diagnostic, therapeutic, and monitoring approach to neurosyphilis, considering whether there is positivity or not for the human immunodeficiency virus. Syphilis is a sexually transmitted notifiable disease, known as the great imitator. In around 30% of cases of untreated disease, there is a persistent central nervous system infection. Neur...

Date: 2024   |   Origin: Acta Médica Portuguesa

Management of Cytomegalovirus Infection in Allogeneic Hematopoietic Stem Cell T...

Silva, Fernando; Martins, António; Ferraz, Paula; Lopes, Diogo; Bastos, Juliana; Joana Araújo, Joana Araújo; Trigo, Fernanda; Pinto, Ricardo

Cytomegalovirus (CMV) is a type of double-stranded deoxyribonucleic acid virus belonging to the herpesviridae family. Following a primary infection, the virus becomes latent in various types of white blood cells. Cytomegalovirus infection can remain latent or become active, especially in immunocompromised individuals, such as those undergoing hematopoietic stem cell transplantation (HSCT), where CMV reactivatio...

Date: 2024   |   Origin: Acta Médica Portuguesa

Schizophyllum commune sphenoidal sinusitis as presentation of a non-Hodgkin Lym...

Filipe, Rita; Caldas, João Paulo; Soares, Neuza; Sabino, Raquel; Veríssimo, Cristina; Silva, Roberto; Silva-Pinto, André; Tavares, Margarida

Schizophyllum commune is a basidiomycetes worldwide distributed that has emerged as cause of invasive infections in immunosuppressed patients. We present a case of a man who was simultaneously diagnosed with a small cell non-Hodgkin lymphoma and a sphenoid sinusitis by S. commune. Intraoperative observation and histology description were crucial to consider an alternative diagnosis to mucormycosis suggested by ...


Neurological Manifestations and COVID-19

Costa, Andreia; Silva-Pinto, André

N/a.; N/a.

Date: 2020   |   Origin: Acta Médica Portuguesa

Protocol for the Prevention of Infections Related to the Treatment of Hematolog...

Silva-Pinto, André; Rocha-Pereira, Nuno; Andrade, Joaquim; Sarmento, António; Santos, Lurdes

Patients with haematological malignancies have a higher incidence of infection compared with the general population. Several factors contribute to this but specially chemotherapy drugs carry different and specific infectious risks. This protocol discusses the prevention of infections in patients who will undergo chemotherapy for the treatment of haematological malignancies. It is divided into: study prior to th...

Date: 2018   |   Origin: Acta Médica Portuguesa

The role of major histocompatibilit y complex in the progression of HIV infection.

Silva-Pinto, André; Santos, Maria Lurdes

Despite being uncommon, there is a small group of HIV infected that, even without treatment, do not evolve to AIDS. Several theories have been proposed over time trying to explain this phenomenon. This article addresses the role of HLA in the TC modulation.Review the literature about the role of MHC in the progression of HIV infection and identify which HLA has a greater role in the progression of HIV infection...

Date: 2011   |   Origin: Acta Médica Portuguesa

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