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How distinct Autism and Schizotypal trait dimensions influence neural predictiv...

Mazer, Prune; Pasion, Rita; Fontes, Melissa; Pires, Cristiana; Silveira, Celeste; Fernando Ferreira-Santos; Mazer, Prune

The Predictive Processing (PP) framework provides a compelling model for understanding the neural mechanisms underlying autism spectrum disorders (ASD) and schizophrenia spectrum disorders (SSD). In this study, we developed visual and auditory oddball tasks with two levels of target detection difficulty to effectively elicit event-related potential (ERP) components. A total of 122 participants from the communit...


Systematic review and meta-analysis of the visual mismatch negativity in schizo...

Mazer, Prune; Carneiro, Fabio; Domingo, Juan; Pasion, Rita; Silveira, Celeste; Ferreira-Santos, Fernando

Mismatch negativity (MMN) is an event-related potential component automatically elicited by events that violate predictions based on prior events. To elicit this component, researchers use stimulus repetition to induce predictions, and the MMN is obtained by subtracting the brain response to rare or unpredicted stimuli from that of frequent stimuli. Under the Predictive Processing framework, one increasingly po...


Autistic traits and event-related potentials in the general population: A scopi...

Mazer, Prune; Garcez, Helena; Macedo, Inês; Pasion, Rita; Silveira, Celeste; Sempf, Frederieke; Ferreira-Santos, Fernando

Differences in short and long-latency Event-Related Potentials (ERPs) can help us infer abnormalities in brain processing, considering early and later stages of stimuli processing across tasks and conditions. In autism research, the adult population remains largely understudied compared to samples at early stages of development. In this context, this scoping review briefly summarises what has been described in ...


Schizophreniform Disorder Related Hospitalizations: A Clinical and Demographic ...

Teixeira da Cunha, Inês; Silveira, Celeste; Freitas, Alberto; Gonçalves Pinho, Manuel

Introduction: Schizophreniform disorder manifests itself with similar symptoms to schizophrenia, but it is distinguished from the latter by its shorter duration, varying between at least one and six months. This study aimed to describe and analyze schizophreniform disorder related hospitalizations in a national hospitalization database.Methods: We planned a descriptive retrospective study using a nationwide hos...

Date: 2024   |   Origin: Acta Médica Portuguesa

Abnormal habituation of the auditory event-related potential P2 component in pa...

Mazer, Prune; Macedo, Inês; Paiva, Tiago O.; Ferreira-Santos, Fernando; Paison, Rita; Barbosa, Fernando; Almeida, Pedro; Silveira, Celeste

Auditory event-related potentials (ERP) may serve as diagnostic tools for schizophrenia and inform on the susceptibility for this condition.Particularly, the examination of N1 and P2 components of the auditory ERP may shed light on the impairments of information processing streams in schizophrenia. However, the habituation properties (i.e., decreasing amplitude with the repeated presentation of an auditory stim...


Mental health of college students: experience of the university psychiatric out...

Silveira, Celeste; Norton, Andreia; Brandão, Isabel; Roma-Torres, António

The mental health of college students has been raising major awareness, due to the increased prevalence and severity of psychiatric disorders in this population. Higher education is associated with significant stressors that contribute to the development of mental health disturbances, and most college students are in the high-risk age group for the emergence of symptoms of major psychiatric disorders. Early dia...

Date: 2011   |   Origin: Acta Médica Portuguesa

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