3 documents found, page 1 of 1
Are General anesthetics neurotoxic?
Batista, Hermes Melo Teixeira; Silveira, Gylmara Bezerra de Menezes; Sampaio, Leonardo Araújo; Bezerra, Italla Maria PinheiroIntroduction: General anaesthesia has been used worldwide since its first public demonstration with ether in 1846. Until a little more than a decade ago, it was believed that the anaesthetic state was limited to the period of exposure. Studies in rats, pigs, and rhesus monkeys have shown that almost all general anaesthetics accelerate the apoptotic process in neurones, oligodendrocytes, and glial cells. Objecti...
Learning disorders related to exposure to general anesthetic in children
Batista, Hermes Melo Teixeira; Pinheiro, Woneska Rodrigues; Silveira, Gylmara Bezerra de Menezes; Borges, Karina Morais; Pita Neto, Ivo CavalcanteBackground: There are many animal studies demonstrating increased neuroapoptose in the first periods of development, especially in stronger neural development regions. In young cobais neuroapoptose also noted, however, more localized area as the dentate nucleus and the olfactory bulb of the brain regions that show sinaptogênse even in adulthood and is responsible for learning. Objective: To describe the current...
Acute abdomen in a patient with haemophilia A: a case study
Batista, Hermes Melo Teixeira; Silveira, Gylmara Bezerra de Menezes; Pita Neto, Ivo Cavalvante; Pinheiro, Woneska RodriguesBackground: Haemophilia A is a hereditary haemorrhagic disorder that can cause bleeding in the intestinal loops and, on rare occasions, simulate an acute surgical abdomen. Careful assessment of coagulation must be performed in these patients, followed by an attempt to correct the dysfunctions. Often, the administration of the deficient factor is sufficient to resolve the problem, avoiding unnecessary surgeries....