18 documents found, page 1 of 2
Pseudomonas mendocina Isolated from Anopheles Midguts has a Greater Potential t...
Marques, Margarida; Pobre, Vania; Costa, Sofia Santos; Pinto, Sandra N.; Silveira, HenriqueMalaria remains the most prevalent vector-borne disease. Manipulating the Anopheles midgut microbiota offers a promising malaria control strategy. Biofilm-forming Pseudomonas spp. may reduce Plasmodium infection in Anopheles mosquitoes because bacterial biofilms at the midgut epithelium may restrict the ookinete movement; therefore, it has a potential application as a malaria transmission blocking tool. Thus, t...
Knowledge, attitude and practice in high endemic settings for malaria
Lequechane, Joaquim Domingos; Chale, Falume; Azevedo, Nicole; Abílio, Ana Paula; Muanido, Alberto Gabriel; Gonçalves, Luzia; Manuel, João LuísBackground: Malaria remains a public health threat globally, mainly in African countries. Despite the progress made over the years, its control and elimination by 2030 appear to be a challenge. The community perspective on factors contributing to malaria burden is essential to develop preventive measures adapted to local contexts. Understanding the transmission rates, symptoms, prevention and treatment of malar...
Drug resistance profile and clonality of Plasmodium falciparum parasites in Cap...
Da Veiga Leal, Silvania; Ward, Daniel; Campino, Susana; Benavente, Ernest Diez; Ibrahim, Amy; Claret, Tânia; Isaías, Varela; Monteiro, DavidsonCape Verde is an archipelago located off the West African coast and is in a pre-elimination phase of malaria control. Since 2010, fewer than 20 Plasmodium falciparum malaria cases have been reported annually, except in 2017, when an outbreak in Praia before the rainy season led to 423 autochthonous cases. It is important to understand the genetic diversity of circulating P. falciparum to inform on drug resistan...
A blood-free diet to rear anopheline mosquitoes
Marques, Joana; Cardoso, João CR; Félix, Rute C.; Power, Deborah; Silveira, HenriqueMalaria research requires large-scale breeding and production conditions for mosquitoes (Anopheles spp.) in captivity. The sustainable and reliable production of mosquitoes is currently inhibited by the supply of fresh vertebrate blood. Alternatives to blood are required to promote efficient control strategies for malaria and other vector borne diseases that are transmitted by blood feeding insects. With this i...
Laboratory services contribution to supporting public health and health service...
Vieira, Marisa Luísa; Rodrigues, Liliana; Almeida, Fernando; Fortes, Filomeno; de Sousa, Germano; Monteiro, Sandra; Silveira, Henrique; Viveiros, MiguelObjective: To promote the debate on the importance of the laboratory services in supporting public health and health services in Portuguese-speaking countries, from a global and One Health perspective. Methods: literature review, analysis of the preparatory papers for the 5th Tropical Medicine National Congress, presentations by speakers from Cape Verde, Angola and Portugal and the ensuing debate. Res...
INTERAÇÃO Plasmodium/Anopheles: UM MISTÉRIO POR RESOLVER?
Custódio, Ana; Silveira, Henrique; Gouveia de Almeida, António Paulo.
More than half a century in the research of malaria in IHMT
Arez, Ana Paula; Silveira, Henrique; Nogueira, FátimaMalaria is a parasitic infection transmitted by Anopheles mosquitoes. Five species of the genus Plasmodium cause disease in humans: P. vivax, P. malariae, P. ovale, P. knowlesi e P. falciparum being the last, the one that causes most mortality and morbidity. During 1950s and early 1960s, the global eradication of malaria was believed possible, but the successively implemented eradicationprogrammes failed and er...
VETORES E HOSPEDEIROS INTERMEDIÁRIOS INVERTEBRADOS
Silveira, Henrique; Belo, SilvanaThe diseases t ransmit ted by arthropods and other invertebrate hosts represent an enormous burden to human and animal health, if we consider that 3.3 billion people are at risk of acquiring malaria, and that , in 2010, malaria deaths were est imated at 655000 (WHO, 2012), that schistosomiasis and geohelminthiasis affect two billion humans, causing morbidity to 300 million (WHO, 2006), and that 350 million peop...
Fresh-blood-free diet for rearing malaria mosquito vectors
Marques, Joana; Cardoso, João CR; Felix, Rute C.; Santana, Rosa A. G.; Guerra, Maria das Graças Barbosa; Power, Deborah; Silveira, HenriqueMosquito breeding depends on the supply of fresh vertebrate blood, a major bottleneck for large-scale production of Anopheles spp. Feeding alternatives to fresh blood are thus a priority for research, outdoor large-cage trials and control interventions. Several artificial meal compositions were tested and Anopheles oogenesis, egg laying and development into the next generation of adult mosquitoes were followed....
Polymerase chain reaction-based method for the identification of Leishmania (Vi...
Prestes, Suzane Ribeiro; Guerra, Jorge Augusto de Oliveira; Romero, Gustavo Adolfo Sierra; Magalhães, Laylah Kelre Costa; Santana, Rosa Amelia GonçalvesIntroduction: in the Americas, mucosal leishmaniasis is primarily associated with infection by Leishmania (Viannia) braziliensis. However, Leishmania (Viannia) guyanensis is another important cause of this disease in the Brazilian Amazon. In this study, we aimed at detecting Leishmaniadeoxyribonucleic acid (DNA) within paraffin-embedded fragments of mucosal tissues, and characterizing the infecting parasite spe...