3 documents found, page 1 of 1
The impact of Hafnia alvei HA4597™ on weight loss and glycaemic control after b...
Ismael, S; Vaz, C; Durao, C; Silvestre, MP; Calhau, C; Teixeira, D; Marques, CBackground Subjects with obesity exhibit changes in gut microbiota composition and function (i.e. dysbiosis) that contribute to metabolic dysfunction, including appetite impairment. Although bariatric surgery is an effective treatment for obesity with a great impact on weight loss, some subjects show weight regain due to increased energy intake after the surgery. This surgery involves gut microbiota changes tha...
A Pilot Study on the Metabolic Impact of Mediterranean Diet in Type 2 Diabetes:...
Ismael, S; Silvestre, MP; Vasques, M; Araújo, JR; Morais, J; Duarte, MI; Pestana, D; Faria, A; Pereira-Leal, JB; Vaz, J; Ribeiro, P; Teixeira, DThe Mediterranean diet (MD) has been recommended for type 2 diabetes (T2D) treatment. The impact of diet in shaping the gut microbiota is well known, particularly for MD. However, the link between MD and diabetes outcome improvement is not completely clear. This study aims to evaluate the role of microbiota modulation by a nonpharmacological intervention in patients with T2D. In this 12-week single-arm pilot st...
Regulatory interactions between the metabolic sensors SIRT1 and AMPK in modulat...
Silvestre, MPBoth genetic and environmental influences determine the risk of developing type 2 diabetes mellitus (T2DM). Epidemiological studies indicate that factors influencing the prevalence of T2DM include lifestyle (e.g. inactivity and dietary macronutrient composition), obesity and age. Interestingly maternal protein restriction (Maternal Low Protein; MLP) generates low birth weight (LBW) offspring, who develop insuli...