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Age-Related Normative Data and Percentile Ranges for Serum Neurofilament Light ...

Spínola, Anuschka; Tábuas-Pereira, Miguel; Leitão, Maria João; Bernardes, Catarina; Lima, Marisa; Durães, João; Freitas, Sandra; Santana, Isabel

Introduction: Blood-based neurofilament light chain (NfL), a neuronal cytoskeleton protein, has proven to be a dynamic and robust biomarker for neurodegeneration. The influence of age on NfL levels has been extensively documented in cerebrospinal fluid studies, with blood quantification showing similar trends. To aid the clinical interpretation of NfL values, it is crucial to establish normal reference interval...

Date: 2026   |   Origin: SINAPSE
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