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Unraveling the significance of DGCR8 and miRNAs in thyroid carcinoma

Rodrigues, Lia; Paula, Arnaud Da Cruz; Soares, Paula; Vinagre, João

MicroRNAs (miRNAs) act as negative regulators for protein-coding gene expression impacting cell proliferation, differentiation, and survival. These miRNAs are frequently dysregulated in cancer and constitute classes of blood-based biomarkers useful for cancer detection and prognosis definition. In thyroid cancer (TC), the miRNA biogenesis pathway plays a pivotal role in thyroid gland formation, ensuring proper ...

Date: 2024   |   Origin: Repositório Científico do Instituto Politécnico do Porto
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