21 documents found, page 1 of 3
Study Of The Prevalence Of Hypertension In Children And Adolescents In Lisbon A...
Simão, Carla; Glória, Joana; Torres Oliveira, Sara; Deuchande, Sofia; Abranches, Margarida; Correia, Susana; Nunes, Paula; Teodoro, FilomenaIntroduction: Hypertension (HTN) is an important risk factor for cardiovascular disease (CVD) at any age. Its prevalence in children is estimated at 3-5%. The knowledge of its prevalence allows for the adequacy of control, treatment and prevention measures, to decrease the morbidity and mortality associated with CVD. Objectives: To assess the prevalence of hypertension in school-age children and adolescents and...
Osimertinib: A Game-Changer in Stage IV EGFR-Driven Lung Cancer
Silva, Sofia; Duarte, Joana; Simão, Carla; Felizardo, MargaridaLung cancer has a high mortality rate; however, treatment with tyrosine kinase inhibitors targeting specific molecular alterations has significantly improved the survival of patients with advanced or metastatic non-small cell lung carcinoma (NSCLC). EGFR mutations are present in approximately 15% of NSCLC cases. Osimertinib was approved in Portugal by Infarmed (Portuguese Medicines Agency) in 2021 as a first-li...
Estudo da Prevalência da Hipertensão Arterial em Crianças e Adolescentes na Reg...
Simão, Carla; Glória, Joana; Torres Oliveira, Sara; Deuchande, Sofia; Abranches, Margarida; Correia, Susana; Nunes, Paula; Teodoro, FilomenaIntrodução: A hipertensão arterial (HTA) é um fator de risco importante de doença cardiovascular (DCV) em qualquer idade. Estima-se uma prevalência na criança de 3-5%. O conhecimento da sua prevalência permite adequar medidas de controlo, tratamento e prevenção, procurando diminuir a morbilidade e mortalidade associadas à DCV. Objetivos: Avaliar a prevalência da HTA em crianças e adolescentes em idade escolar e...
AT LAST! It was not a progression!
Paulinetti Camara, Raquel; Lopes, Kelly; Barbosa, Miguel; Sucena, Inês; Simão, Carla; Mota, Paulo; Matias, Dina; Sequeira, Telma; Almodovar, TeresaIntroduction: Nivolumab is approved in Portugal for non-small cell metastatic lung cancer, as one of the indications, after progressing on chemotherapy. As an immune checkpoint inhibitor (ICI) immune-related adverse events (irAE) are possible reactions. Case report: A 64-year-old man with stage III lung adenocarcinoma who progressed after chemoradiotherapy and first line metastatic chemotherapy started nivoluma...
DOES BARIATRIC SURGERY HAVE A ROLE IN THE METABOLIC SYNDROME IN PEDIATRICS?
Urbano, Filipa; Simão, CarlaIntroduction: Metabolic syndrome is the combination of arterial hypertension, obesity, visceral adiposity, insulin resistance and dyslipidemia. These cardiovascular risk factors influence each other and the treatment of this syndrome as a whole is essential for the control of each of these factors. Non-pharmacological measures are the mainstay of treatment, followed by pharmacological therapy. Nevertheless, bar...
Silent Changes In Blood Pressure In Sickle Cell Anemia - Clinical Case Of A Sev...
Urbano, Filipa; Ventura, Ana; Ferrão, Anabela; Simão, CarlaRecent studies indicate that high blood pressure is not uncommon in sickle cell disease patients, largely manifested by masked hypertension, and the specific endothelial lesions that occur in this disease may put them at greater risk of acute and chronic cardiovascular events. Posterior reversible encephalopathy syndrome is a potentially serious acute neurological manifestation of an hypertensive crisis and thi...
NEONATAL RENOVASCULAR HYPERTENSION AND TARGET-ORGAN DAMAGE
Cristóvão Ferreira, Ana; Rebelo, Mónica; Lobo, Luísa; Simão, CarlaIntroduction: Arterial hypertension in the neonatal period is defined by blood pressure values above the 95th percentile, taking into account post-menstrual age. At this age group, it is usually due to renal disease (parenchymal or renovascular diseases). The target-organ lesion may be present at these ages; however, it can be potentially reversible, if the diagnosis and the therapeutic intervention are made in...
Infantile Nephropathic Cystinosis: Diagnosis and Treatment of a Systemic Disease
Urbano, Filipa; Salgado, Catarina; Leal, Inês; Vilarinho, Laura; Simão, CarlaCystinosis is a rare autosomal recessive lysosomal storage disorder leading to end-stage renal disease and many extra-renal complications. Seventeen month old girl with normal development until 14 months, when parents noted polydipsia, polyuria and growth stagnation. Investigations performed in a tertiary setting were compatible with Fanconi Syndrome and X-ray with rickets. The hypothesis of diagnosis of infant...
Admission of Lung Cancer Patients to Intensive Care Units
Carreto, Luis; Simão, Carla; Silveira, Miguel; Almeida, Maria AméliaN/a.; N/a.
Unilateral renal agenesis and uterine anomalies: how and when can we make this ...
Gaspar, Joana; Ferreira, Natália; Lobo, Luísa; Simão, CarlaA 12-year-old female with a prenatal diagnosis of left kidney agenesis was hospitalized with a history of four months of recurrent abdominal pain and dysmenorrhea after menarche. Imaging investigation revealed a gynecological malformation associated with Müllerian developmental defects – duplicated uterus with an obstructed left hemi-uterus filled with hematic content (haematometra), one cervix and a normal vag...