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Symptom Clusters in Patients With Advanced Cancer: a Prospective Longitudinal C...

Simão, D; Barata, P; Alves, M; Papoila, AL; Oliveira, S; Lawlor, P

This study's purpose was to assess symptom cluster (SC) stability during disease progression and determine their strength of association with survival in patients with advanced cancer . Consecutively eligible patients with advanced cancer not receiving cancer-specific treatment and referred to a Tertiary Palliative Care Clinic were enrolled in a prospective cohort study. At first consultation (D0) and in subseq...


Myocardial Work Brings New Insights into Left Ventricular Remodelling in Cardio...

Vaz Ferreira, V; Mano, T; Cardoso, I; Coutinho Cruz, M; Branco, LM; Almeida-Morais, L; Timóteo, AT; Galrinho, A; Castelo, A; Garcia Brás, P; Simão, D

Serial transthoracic echocardiographic (TTE) assessment of 2D left ventricular ejection fraction (LVEF) and global longitudinal strain (GLS) are the gold standard screening methods for cancer therapeutics-related cardiac dysfunction (CTRCD). Non-invasive left ventricular (LV) pressure-strain loop (PSL) provides a novel method of quantifying myocardial work (MW) with potential advantages to evaluate the impact o...


What Has Changed During the COVID-19 Pandemic? - The Effect on an Academic Brea...

Simão, D; Sardinha, M; Reis, AF; Spencer, AS; Luz, R; Oliveira, S

Introduction: One year ago, Portugal entered its first lockdown because of the coronavirus disease-2019 (COVID-19) pandemic. The impact of this on delays in cancer diagnosis and treatment is a major concern, which may negatively affect the outcomes of these patients. Materials and methods: This retrospective, single-center analysis compared the clinical and pathological characteristics of breast cancer (BC) pat...


Full Recovery of a Stage IV Cancer Patient Facing COVID-19 Pandemic

Parmanande, A; Simão, D; Sardinha, M; Palma dos Reis, AF; Spencer, AS; Barreira, JV; Luz, R

Coronavirus disease 2019 (COVID-19), first recognized in Wuhan, China, was recently declared a global pandemic by the World Health Organization (WHO). Advanced age and comorbid disease, well-known characteristics in the solid tumor population, have been reported as risk factors for severe disease and death. Cancer-related immunosuppression and its treatments also seem to play an active role in the prognosis, re...


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