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Concomitant Nitrofurantoin-Induced Autoimmune Hepatitis and Interstitial Lung D...

Matos,Andreia Carvalho de; Macedo,Cristiane Pais; Mendes,Patrícia Afonso; Cipriano,Maria Augusta; Paiva,Artur; Simão,Adélia

Abstract Antibiotics are known to cause adverse reactions, but multiple organ involvement associated with nonspecific symptoms can lead to a delay in diagnosis. A definitive correlation between each toxin and its effects is difficult to establish due to concomitant potential toxins in the circulation. This article highlights an uncommon case of concomitant nitrofurantoin-induced autoimmune hepatitis and lung fi...

Date: 2022 | Origin: SciELO Portugal

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Perfusion Magnetic Resonance as a Biomarker for Sorafenib-Treated Advanced Hepa...

Campos,Marta; Candelária,Isabel; Papanikolaou,Nickolas; Simão,Adélia; Ferreira,Carlos; Manikis,Georgios C.; Caseiro-Alves,Filipe

Background: Sorafenib is the currently recommended therapy in patients with advanced hepatocellular carcinoma (HCC). Among the several biomarkers available for the evaluation of the therapeutic response and prognosis, there is perfusion magnetic resonance imaging (p-MRI) that, through measurement of the vascular permeability unit (ktrans), may retrieve useful information regarding the microvascular properties o...

Date: 2019 | Origin: SciELO Portugal

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Hepatocellular Carcinoma: Portuguese Data in Chronic Hepatitis B Patients on An...

Simão,Adélia

Date: 2016 | Origin: SciELO Portugal

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Hepatite autoimune: os critérios simplificados são menos sensíveis?

Correia,Lurdes; Monteiro,Rita; Simão,Adélia; Louro,Emília; Santos,Arsénio; Carvalho,Armando

Introdução: A hepatite autoimune (HAI) tem apresentação clínica variável e o seu reconhecimento pode ser difícil. Os critérios de diagnóstico do Grupo Internacional de HAI, inicialmente propostos com fins científicos, são complexos na prática clínica. Em 2008, Henes et al. Propuseram critérios de diagnóstico simplificados (CDS), com valores preditivos positivos e negativos na ordem dos 90%, mas necessitando de ...

Date: 2013 | Origin: SciELO Portugal

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