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Production of an extract rich in alpha-tomatine from green tomatoes by subcriti...
Faria-Silva, Catarina; Pedras, Bruno; Costa, Nuno; Carvalheiro, Manuela; Simões, Sandra; Simões, PedroResearch Institute for Medicines\u2014iMed.ULisboa is funded by FCT through project UID 04138. Publisher Copyright: © 2025 The Authors.; Green tomatoes, a by-product of agro-food industry, are rich in the glycoalkaloid alpha-tomatine. This compound presents health benefits including anti-inflammatory and fungicide properties. Subcritical water extraction (SWE), a green and sustainable process, was used to obtai...
Optimization of Nanoencapsulation of Codium tomentosum Extract and Its Potentia...
Costa, Micaela; Soares, Cristina; Silva, Aurora; Barroso, Maria Fátima; Simões, Pedro; Ferreira, Mariana; Gameiro, Paula; Grosso, ClaraFunding Information: This work was financed by FEDER—Fundo Europeu de Desenvolvimento Regional funds through the COMPETE 2020—Operacional Programme for Competitiveness and Internationalisation (POCI), and by Portuguese funds through FCT—Fundação para a Ciência e a Tecnologia in the framework of the project POCI-01-0145-FEDER-030240—PTDC/OCE-ETA/30240/2017—SilverBrain—From Sea to Brain: Green Neuroprotective Ext...
In Vitro, Ex Vivo, and In Vivo Evaluation of Silver Nanoparticles Synthesized U...
Cunha, Daniela; Faria-Silva, Catarina; Carvalho, Filomena A.; Ascensão, Lia; Simões, Pedro; Carvalheiro, Manuela; Simões, SandraPublisher Copyright: © 2024 by the authors.; Biogenic silver nanoparticles (AgNP) are among the fastest-growing nanomaterials due to the simplicity, efficiency, and sustainability of their biosynthesis using phytochemicals as reducing and coating agents. The agro-food industry generates large quantities of organic waste, a renewable source of biomolecules for AgNP biosynthesis. The main objective of this work w...
Evaluation of the Biological Potential of Himanthalia elongata (L.) S.F.Gray an...
Gomes, Inês; Rodrigues, Helena; Rodrigues, Carla; Marques, Marta; Paíga, Paula; Paiva, Alexandre; Simões, Pedro; Fernandes, Virgínia CruzThis work was financed by FEDER—Fundo Europeu de Desenvolvimento Regional funds through the COMPETE 2020—Operacional Programme for Competitiveness and Internationalisation (POCI). Publisher Copyright: © 2022 by the authors. Licensee MDPI, Basel, Switzerland.; Neuroprotection is a need that remains unmet in treating chronic neurodegenerative disorders, despite decades of extensive research. To find new neuroprot...
Carta com notícias do reino de França e novidades sobre a armada de Afonso de A...
Simões, Pedro[c. 1513, s.l.] Carta enviada ao Rei de Portugal acerca da entrega dos gatos e papagaios ao Rei e Rainha de França e outras novidades do reino. Inclui também notícia da armada de Afonso de Albuquerque. [c. 1513, s.l.] Letter sent to the King of Portugal regarding the delivery of cats and parrots, as well as other novelties from the kingdom, to the King and Queen of France. It also includes news of Afonso de Alb...
Carta testemunhável elaborada a pedido de Manuel de Mesquita sobre as rendas do...
Simões, PedroGoa, 1555, dezembro, 19 Carta testemunhável feita a petição de Manuel de Mesquita, sobre as rendas do guazilado de Ormuz. Goa, 19 December 1555 Authenticated letter written upon request from Manuel de Mesquita, about the revenues of the vizierate of Hormuz.
Carta de D. joão III ao capitão de Ormuz D. Pedro de Castelo Branco agradecendo...
Simões, Pedro1542, Lisboa, março, 18 Carta de resposta enviada a mando de D. João III ao capitão de Ormuz D. Pedro de Castelo Branco em que agradece o seu serviço e exorta à colaboração entre o governador da Índia e o capitão de Ormuz. 1542, Lisbon, 18 March Letter of reply sent upon orders from King João III to the captain of Hormuz, D. Pedro de Castelo Branco, in which he thanks him for his service and urges cooperation b...
Multi-step subcritical water extracts of fucus vesiculosus l. And codium toment...
Soares, Cristina; Paíga, Paula; Marques, M. Manuel B.; Neto, Tânia; Carvalho, Ana Paula; Paiva, Alexandre; Simões, Pedro; Costa, Leonor; Bernardo, AnaPO-CI-01-0145FEDER-030240; Mental health and active aging are two of the main concerns in the 21st century. To search for new neuroprotective compounds, extracts of Codium tomentosum Stackhouse and Fucus vesiculosus L. were obtained through multi-step (four step) subcritical water extraction using a temperature gradient. The safety assessment of the extracts was performed by screening pharmaceutical compounds a...
Evaluating the presence of lycopene-enriched extracts from tomato on topical em...
Costa, Ana M.; Marques, Marta; Congiu, Franca; Paiva, Alexandre; Simões, Pedro; Ferreira, António; Bronze, Maria Rosário; Marto, JoanaUIDB/QUI/50006/2020 UIDB/04138/2020 UIDP/04138/2020 PTDC/SAU-SER/30197/2017LISBOA-01-0145-FEDER-030197 IF/01146/2015; One of the new trends of personal care industry is the use of organic ingredients derived from nature, in particular, from food-processing residues with proven efficacy. Lycopene is a carotenoid responsible for the red color of several fruits, namely tomato, whose antioxidant and photoprotective...
Subcritical water extraction and hydrolysis of cod (Gadus morhua) frames to pro...
Melgosa, Rodrigo; Marques, Marta; Paiva, Alexandre; Bernardo, Ana; Fernández, Naiara; Sá-Nogueira, Isabel; Simões, PedroUIDB/QUI/50006/2020 UIDP/04378/2020 UIDB/04378/2020 PTDC/ASP-PES/28399/2017 UIDB/04462/2020 UIDP/04462/2020 IF/01146/2015; The valorization of Atlantic cod (Gadus morhua) frames from a filleting industry was investigated using subcritical water extraction and hydrolysis (SBW) at different temperatures (90, 140, 190 and 250◦C) and 100 bar to obtain extracts rich in proteins, peptides and amino acids. Up to 57.7 ...