15 documents found, page 1 of 2

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Multimorbidity patterns and associated factors in a megacity: a cross-sectional...

de Aguiar, RG; Simões, D; Castro, SS; Goldbaum, M; Cesar, CLG; Lucas, R

OBJECTIVE: To identify empirical patterns of multimorbidity and quantify their associations with socioeconomic, behavioral characteristics, and health outcomes in the megacity of São Paulo. METHODS: This was a cross-sectional study conducted through household interviews with residents aged 20 years or older in urban areas (n = 3,184). Latent class analysis was used to identify patterns among the co-existence of...


The HepHIV 2023 Madrid conference: A call to action for political leadership in...

Simões, D; Raben, D; Moran, AB; Imaz, A; Stengaard, AR; Raahauge, A; Sullivan, AK; Vaughan, E; Brännström, J; De Baetselier, I; Platteau, T; Casabona, J

Introduction and Objectives: The HepHIV 2023 Conference, held in Madrid in November 2023, highlighted how Europe is not on track to meet the United Nations (UN) sustainable development goals and Joint UN Programme on HIV/AIDS (UNAIDS) targets. This article presents the outcomes of the conference, which focus on ways to improve testing and linkage to care for HIV, viral hepatitis, and other sexually transmitted ...


Preparing the certification of software as a medical device: a european regulat...

Lopes, IE; Pinto, JF; da Silva, HP; Chambel, G; Clemente, C; Silva, DCF; Montes, AM; Simões, D

Purpose: The primary objective of this study is the preparation of the certification of the Clynx® Platform, a physiotherapy software, as a Class IIa medical device software in accordance with the regulatory framework outlined in Medical Device Regulation 2017/745 (MDR). Methods: The methodology involves a comprehensive analysis of European Union medical device regulations and guidelines, with a specific focus ...


HIV-1-Transmitted Drug Resistance and Transmission Clusters in Newly Diagnosed ...

Pingarilho, M; Pimentel, V; Miranda, M; Silva, AR; Diniz, A; Ascenção, B; Piñeiro, C; Koch, C; Rodrigues, C; Caldas, C; Morais, C; Faria, D

Objective: To describe and analyze transmitted drug resistance (TDR) between 2014 and 2019 in newly infected patients with HIV-1 in Portugal and to characterize its transmission networks. Methods: Clinical, socioepidemiological, and risk behavior data were collected from 820 newly diagnosed patients in Portugal between September 2014 and December 2019. The sequences obtained from drug resistance testing were us...


Late diagnosis of HIV: An updated consensus definition

Croxford, S; Stengaard, AR; Brännström, J; Combs, L; Dedes, N; Girardi, E; Grabar, S; Kirk, O; Kuchukhidze, G; Lazarus, JV; Noori, T; Pharris, A

Introduction: In recent years, HIV testing frequency has increased, resulting in more people being diagnosed during seroconversion with a temporarily low CD4 count. Using the current consensus definition of late HIV presentation ('presenting for care with a CD4 count < 350 cells/μL or an AIDS-defining event, regardless of CD4 count') these individuals would be incorrectly assigned as being diagnosed late. Metho...


A call to action to reclaim focus on testing and early treatment for HIV, viral...

Stengaard, AR; Raben, D; Leite, RB; Seyler, T; Lazarus, JV; Lambert, J; Collins, B; Attawell, K; Raahauge, A; Rockstroh, JK; Simões, D

We present the outcomes of the HepHIV 2021 Lisbon & virtual conference held on 5-7 May 2021, including a Call to Action addressing policy and practice implications in the field of earlier and integrated testing for HIV, viral hepatitis, STI and TB and in light of lessons learned from the COVID-19 pandemic. Conference presentations showed that combination prevention and integrated testing and care models for mul...


National multi-stakeholder meetings: a tool to support development of integrate...

Simões, D; Matulionyté, R; Stoniene, L; Wysocki, P; Kowalska, J; Gasbarrini, N; Cosmaro, L; Blažić, TN; Dišković, A; Dominković, Z; Jovovic, I

Background Country level policies and practices of testing and care for HIV, viral hepatitis and sexually transmitted infections are lagging behind European recommendations on integration across diseases. Building on previous experiences and evidence, the INTEGRATE Joint Action arranged four national stakeholder meetings. The aim was to foster cross-disciplinary and cross-disease collaborations at national leve...


HIV seroprevalence in five key populations in Europe: a systematic literature r...

Stengaard, AR; Combs, L; Supervie, V; Croxford, S; Desai, S; Sullivan, AK; Jakobsen, SF; Santos, Q; Simões, D; Casabona, J; Lazarus, JV; de Wit, JBF

Background: In Europe, HIV disproportionately affects men who have sex with men (MSM), people who inject drugs (PWID), prisoners, sex workers, and transgender people. Epidemiological data are primarily available from national HIV case surveillance systems that rarely capture information on sex work, gender identity or imprisonment. Surveillance of HIV prevalence in key populations often occurs as independent st...


Increasing integrated testing in community settings through interventions for c...

Gasbarrini, N; Dubravić, D; Combs, L; Dišković, A; Ankiersztejn-Bartczak, M; Colaiaco, F; Wawer, I; Wysocki, P; Rosińska, M; Marzec-Boguslawska, A

Background: Maximising access to testing by targeting more than one infection is effective in identifying new infections in settings or populations. Within the EU funded Joint Action INTEGRATE, this paper examined the feasibility and impact of expanding integrated testing for HIV, hepatitis C (HCV), chlamydia, gonorrhoea and/or syphilis in four community-based pilots through targeted interventions in Croatia, I...


Knowledge and Use of PEP and PrEP Among Key Populations Tested in Community Cen...

Simões, D; Meireles, P; Rocha, M; Freitas, R; Aguiar, A; Barros, H

Background: Pre-exposure prophylaxis (PrEP) and post-exposure prophylaxis (PEP) have been increasingly available in Europe. Due to the high burden of HIV in key populations, these could benefit from their use. In 2016, in Portugal, an open, non-interval, prospective cohort study was established in a network of 26 community-based voluntary HIV/STI counseling and testing centers. Data collected included questions...


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