9 documents found, page 1 of 1
Production and characterization of electrospun silk fibroin based asymmetric me...
Miguel, Sónia P.; Simões, Déborah; Moreira, André; Sequeira, Rosa Maria Saraiva; Correia, Ilídio Joaquim SobreiraNowadays, wound dressings with improved properties are under development and among them, asymmetric membranes have gained an increasing interest due to their two-layered structure that mimic both the epidermis and dermis layers of the skin. Herein, a new asymmetric membrane was produced using the electrospinning technique. The top layer was produced with silk fibroin (SF) and poly(caprolactone) to reproduce the...
Recent advances on antimicrobial wound dressing: A review
Simões, Déborah; Miguel, Sónia P.; Ribeiro, Maximiano P.; Coutinho, Paula; Mendonça, António G.; Correia, Ilídio J.Skin and soft tissue infections (SSTIs) have high rates of morbidity and mortality associated. Despite the successful treatment of some SSTIs, those affecting the subcutaneous tissue, fascia, or muscle delay the healing process and can lead to life-threatening conditions. Therefore, more effective treatments are required to deal with such pathological situations. Recently, wound dressings loaded with antimicrob...
Electrospun polymeric nanofibres as wound dressings: A review
Miguel, Sónia P.; Figueira, Daniela R.; Simões, Déborah; Ribeiro, Maximiano P.; Coutinho, Paula; Ferreira, Paula; Correia, Ilídio J.Skin wounds have significant morbidity and mortality rates associated. This is explained by the limited effectiveness of the currently available treatments, which in some cases do not allow the reestablishment of the structure and functions of the damaged skin, leading to wound infection and dehydration. These drawbacks may have an impact on the healing process and ultimately prompt patients’ death. For this re...
Recent advances on antimicrobial wound dressing: A review
Simões, Déborah; Miguel, Sónia; Ribeiro, Maximiano; Coutinho, Paula; Mendonça, António; Correia, IlídioSkin and soft tissue infections (SSTIs) have high rates of morbidity and mortality associated. Despite the successful treatment of some SSTIs, those affecting the subcutaneous tissue, fascia, or muscle delay the healing process and can lead to life-threatening conditions. Therefore, more effective treatments are required to deal with such pathological situations. Recently, wound dressings loaded with antimicrob...
Recent advances on antimicrobial wound dressing: A review
Simões, Déborah; Miguel, Sónia; Ribeiro, Maximiano; Coutinho, Paula; Mendonça, António; Correia, IlídioSkin and soft tissue infections (SSTIs) have high rates of morbidity and mortality associated. Despite the successful treatment of some SSTIs, those affecting the subcutaneous tissue, fascia, or muscle delay the healing process and can lead to life-threatening conditions. Therefore, more effective treatments are required to deal with such pathological situations. Recently, wound dressings loaded with antimicrob...
Recent advances on antimicrobial wound dressing: A review
Simões, Déborah; Miguel, Sónia P.; Ribeiro, MP.; Coutinho, Paula Isabel Teixeira Gonçalves; Mendonça, António; Correia, Ilídio Joaquim SobreiraSkin and soft tissue infections (SSTIs) have high rates of morbidity and mortality associated. Despite the successful treatment of some SSTIs, those affecting the subcutaneous tissue, fascia, or muscle delay the healing process and can lead to life-threatening conditions. Therefore, more effective treatments are required to deal with such pathological situations. Recently, wound dressings loaded with antimicrob...
Biofunctionalization of electrospun poly(caprolactone) fibers with Maillard rea...
Simões, Déborah; Miguel, Sónia P.; Correia, I.J.Bacterial colonization of open skin wounds can interfere with the healing process, contributing to an increase in the severity of the wound. To overcome such drawback, wound dressings with an improved bactericidal activity have been developed or are currently under development. Herein, poly(caprolactone) (PCL) nanofibrous membranes functionalized with biosynthesized Maillard reaction products (MRPs) were produc...
Development of a new bioactive membrane to be used for the treatment of skin in...
Simões, DéborahSkin and soft tissue infections (SSTIs) have high rates of morbidity and mortality associated. Despite the successful treatment of some SSTIs, those affecting the subcutaneous tissue, fascia, or muscle delay the healing process and can lead to life-threatening conditions. Therefore, it is fundamental to develop antimicrobial wound dressings to deal with such pathological situations. Recently, wound dressings lo...
Electrospun polymeric nanofibres as wound dressings: A review
Miguel, Sónia P.; Figueira, Daniela Sofia Rodrigues; Simões, Déborah; Ribeiro, MP.; Coutinho, Paula; Ferreira, Paula; Correia, Ilídio Joaquim SobreiraSkin wounds have significant morbidity and mortality rates associated. This is explained by the limited effectiveness of the currently available treatments, which in some cases do not allow the reestablishment of the structure and functions of the damaged skin, leading to wound infection and dehydration. These drawbacks may have an impact on the healing process and ultimately prompt patients’ death. For this re...