15 documents found, page 1 of 2
Circadian and Biological Rhythms in Shift Workers—A Firefighter’s Study
Duarte, I.F.; Pereira, J.; Lima, JPM.; Simões, H.; Pereira, T.; Conde, J.Shift Work contribute to dysregulation of the typical sleep and awake periods that cause circadian distortions, increasing the risk of cardiovascular mortality and morbidity and developing metabolic diseases. Firefighting is a career that demands much of individuals and has a great impact on their health, making it a high-risk job. Objectives: This study aims to characterize shift workers’ blood pressure profil...
Molecular detection of Aspergillus in respiratory samples collected from patien...
Oliveira, M.; Pinto, M.; Simões, H.; Gomes, J.P.; Veríssimo, C.; Sabino, R.Objective: Aspergillosis diagnosis depends on the detection of Aspergillus in biological samples ─ usually using cultural and immunoenzyme techniques ─ but their sensitivity and specificity varies. We aimed to study the prevalence of Aspergillus in patients at higher risk of chronic pulmonary aspergillosis (i.e., HIV-infected patients and individuals with active or previous tuberculosis), and to determine the p...
Gastroenteropancreatic Neuroendocrine Neoplasia Characterization in Portugal: R...
Santos, A.; Vinagre, J.; Soares, P.; Claro, I.; Sanches, A.; Gomes, L.; Fernandes, I.; Catarino, A.; Preto, J.; Pereira, B.; Marques, A.; Rodrigues, F.Background: The incidence of gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) has been increasing in the last five decades, but there is no large-scale data regarding these tumours in Portugal. We conducted a cross-sectional, multicentric study in main Portuguese centers to evaluate the clinical, pathological, and therapeutic profile of GEP-NENs. Methods: From November, 2012, to July, 2014, data from ...
Ageing at work: capacity for the work of ESTeSC teachers
Correia, T.; Simões, H.; Pereira, J.; Telo, E.; Cotrim, T. P.; Figueiredo, J.; Ferreira, A.Introduction: Aging does not necessarily mean a decrease in "ability to work" and that the eventual decline of certain skills related to increasing age are not generalizable, striking, or uniform and can be accelerated or delayed depending on the conditions of work, individuals and, above all, the types of attrition to which the worker is subjected. Objective: To evaluate the work ability index (WAI) of the pro...
Frequency and molecular epidemiology of Aspergillus isolated from patients with...
Oliveira, M.; Simões, H.; Verissimo, C.; Sabino, R.Objective: The aim of this study was to determine the frequency of Aspergillus detected in respiratory samples from a cohort of patients with suspicion of fungal infection of the respiratory tract as well as to determine the susceptibility to azoles of the isolates from the Fumigati section. Methods: A retrospective study was performed involving samples obtained from 16 hospitals covering different districts of...
Dermatophytes’ identification by Matrix-assisted laser desorption ionization-ti...
Verissimo, C.; Simões, H.; Sabino, R.; Simões, D.Objectives: Dermatophytes are a challenging group of fungi that infect the keratinized tissues. The taxonomy of these fungi has changed recently with the reclassification of some species and description of new ones. However, many clinical laboratories still base the identification of dermatophytes on their phenotype. Since dermatophytes are very pleomorphic, macro and micromorphology are often insufficient to r...
Molecular diagnosis of invasive aspergillosis in a child with clinical suspicio...
Sabino, Raquel; Ramos, A.; Simões, H.; Palaré, M.J.; Moreno, R.; Ferrão, A.; Lourenço, F.; Marques, J.G.; Martins, C.; Morais, A.; Verissimo, C.Purpose: Invasive aspergillosis is difficult to manage in immunocompromised patients. We present a clinical case of a 13-year-old boy from Cabo Verde who was transferred to the Hematology Unit of a Central Hospital in Lisbon, Portugal, and diagnosed with aplastic anemia. Weeks after hospital admission, in June 2016, he presented febrile neutropenia with negative blood cultures. In August, the patient showed a n...
Histoplasma var. duboisii in Portugal. African souvenir?
Veríssimo, Cristina; Simões, H.; Sabino, RaquelObjectives: Histoplasmosis is an infection caused by Histoplasma capsulatum. Infections are caused by two varieties: Histoplasma capsulatum var. capsulatum, endemic in North and South America, and Histoplasma capsulatum var. duboisii, endemic in Central and West Africa and Madagascar Island. Variety duboisii has tropism for lymph nodes, skin, and bones, being classically associated with cutaneous lesions. In th...
Aspergillus section Fumigati – Epidemiological trends: a perspective from a Nat...
Sabino, Raquel; Simões, H.; Francisco, M.; Viegas, Carla; Toscano, C.; Batista, J.; Ferreira, T.; Veríssimo, CarlaAspergillus species have emerged as an important cause of life-threatening infections in immunocompromised patients. Aspergillus fumigatus is the most frequent agent of aspergillosis and reports on infections caused by this species or its siblings are becoming more frequent, together with the increasing number of at-risk patients. Nowadays, due to the rising concerns about emerging antifungal resistance, the ep...
Identification of Aspergillus cryptic species in hospital environment
Sabino, Raquel; Viegas, Carla; Veríssimo, Carla; Simões, H.; Brandão, João; Martins, C; Clemons, K. V.; Stevens, D. A.Selected hospital wards, housing patients at higher risk to develop invasive fungal infections, were screened in order to understand the epidemiology and distribution of Aspergillus, especially regarding the presence of cryptic species.Aspergillus species were identified by b-tubulin and calmodulin sequencing, and a high percentage of cryptic species (i.e., not sensu stricto) was found (59%). Sections Usti, Ver...