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Profile of cognitive impairment in late-stage Parkinson's disease

Sousa, Catarina Severiano e; Fabbri, Margherita; Godinho, Catarina; Simões, Rita Moiron; Chendo, Inês; Coelho, Miguel; Martins, Isabel Pavão

Introduction: The profile of cognitive impairment associated with the late stages of Parkinson's disease (LSPD) is rarely reported. Its characterization is necessary to better understand the cognitive changes that occur as the disease progresses and to better contribute to its management.


Profile of cognitive impairment in late-stage Parkinson's disease

Sousa, Catarina Severiano e; Fabbri, Margherita; Godinho, Catarina; Simões, Rita Moiron; Chendo, Inês; Coelho, Miguel; Martins, Isabel Pavão

Introduction: The profile of cognitive impairment associated with the late stages of Parkinson's disease (LSPD) is rarely reported. Its characterization is necessary to better understand the cognitive changes that occur as the disease progresses and to better contribute to its management. Methods: In this cross-sectional study, we characterized the cognitive profile of LSPD patients using the comprehensive asse...


High frequency of psychosis in late-stage Parkinson’s disease

Chendo, Inês; Fabbri, Margherita; Godinho, Catarina; Simões, Rita Moiron; Sousa, Catarina Severiano; Coelho, Miguel; Voon, Valerie; Ferreira, Joaquim J.

Background Psychosis is a frequent non-motor symptom in Parkinson’s disease (PD). Estimates of the frequency of Parkinsońs disease psychosis (PDP) vary widely. Knowledge about the frequency and phenomenology of psychosis in late-stage (LS) PD patients is limited. This study aimed to determine the frequency of psychosis in LSPD patients through clinical diagnostic interview (CDI) (gold standard), according to NI...


High frequency of psychosis in late-stage Parkinson's disease

Chendo, Inês; Fabbri, Margherita; Godinho, Catarina; Simões, Rita Moiron; Sousa, Catarina Severiano; Coelho, Miguel; Voon, Valerie; Ferreira, Joaquim J.

Background: Psychosis is a frequent non-motor symptom in Parkinson’s disease (PD). Estimates of the frequency of Parkinsońs disease psychosis (PDP) vary widely. Knowledge about the frequency and phenomenology of psychosis in late-stage (LS) PD patients is limited. This study aimed to determine the frequency of psychosis in LSPD patients through clinical diagnostic interview (CDI) (gold standard), according to N...


Consenso Português para o diagnóstico e gestão clínica da demência com corpos d...

Monteiro, Ana; Velon, Ana Graça; Rodrigues, Ana Margarida; Oliveira, Ana; Valadas, Anabela; Nóbrega, Camila; Cruto, Catarina; Neutel, Dulce

Lewy body dementia is a common cause of dementia leading to the progressive deterioration of cognitive function and motor skills, behavioral changes, and loss of autonomy, impairing the quality of life of patients and their families. Even though it is the second leading cause of neurodegenerative dementia, diagnosis is still challenging, due to its heterogenous clinical presentation, especially in the early sta...


[Recommendations about Multiple Sclerosis Management during Pregnancy, Partum a...

Batista, Sónia; Martins da Silva, Ana; Sá, Maria José; Sousa, Lívia; De Sá, João; Pedrosa, Rui; Cerqueira, João; Pinheiro, Joaquim; Abreu, Pedro

Multiple sclerosis typically affects young women of reproductive age. Therefore, all healthcare professionals involved in the follow-up of multiple sclerosis patients must be prepared to discuss pregnancy and breastfeeding issues and provide the best possible counselling. However, there are still many doubts and heterogeneous clinical approaches partly due to the lack of consensus and guidelines. Concerning the...


Recommendations about Multiple Sclerosis Management during Pregnancy, Partum an...

Batista, Sónia; Martins da Silva, Ana; Sá, Maria José; Sousa, Lívia; de Sá, João; Pedrosa, Rui; Cerqueira, João; Pinheiro, Joaquim; Abreu, Pedro

Multiple sclerosis typically affects young women of reproductive age. Therefore, all healthcare professionals involved in the follow-up of multiple sclerosis patients must be prepared to discuss pregnancy and breastfeeding issues and provide the best possible counselling. However, there are still many doubts and heterogeneous clinical approaches partly due to the lack of consensus and guidelines. Concerning the...

Date: 2020   |   Origin: Acta Médica Portuguesa

Recomendações sobre a abordagem da esclerose múltipla na gravidez, parto e pós-...

Batista, Sónia; Martins da Silva, Ana; Sá, Maria José; Sousa, Lívia; De Sá, João; Pedrosa, Rui; Cerqueira, João; Pinheiro, Joaquim; Abreu, Pedro

Multiple sclerosis typically affects young women of reproductive age. Therefore, all healthcare professionals involved in the follow-up of multiple sclerosis patients must be prepared to discuss pregnancy and breastfeeding issues and provide the best possible counselling. However, there are still many doubts and heterogeneous clinical approaches partly due to the lack of consensus and guidelines. Concerning the...


A distinct neuromelanin magnetic resonance imaging pattern in parkinsonian mult...

Simões, Rita Moiron; Castro Caldas, Ana; Grilo, Joana; Correia, Daisy; Guerreiro, Carla; Pita Lobo, Patrícia; Valadas, Anabela; Fabbri, Marguerita

Background: Parkinsonian variant of multiple system atrophy is a neurodegenerative disorder frequently misdiagnosed as Parkinson's disease. No early imaging biomarkers currently differentiate these disorders. Methods: Simple visual imaging analysis of the substantia nigra and locus coeruleus in neuromelanin-sensitive magnetic resonance imaging and nigrosome 1 in susceptibility-weighted sequences was performed i...


Recomendações Sobre a Abordagem da Esclerose Múltipla na Gravidez, Parto e Pós-...

Batista, Sónia; Silva, Ana Martins; Sá, Maria José; Sousa, Lívia; De Sá, João; Pedrosa, Rui; Cerqueira, João; Pinheiro, Joaquim; Abreu, Pedro

A esclerose múltipla afeta tipicamente mulheres jovens em idade reprodutiva. Desta forma, todo os profissionais de saúde envolvidos no seguimento destes doentes deverão estar preparados para abordar as questões relacionadas com a gravidez e amamentação e fornecer o melhor aconselhamento possível. No entanto, existem ainda muitas dúvidas e abordagens clínicas heterogéneas em parte devido à ausência de consensos ...


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