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Tofacitinib: An Option for Acute Severe Ulcerative Colitis?
Santos,Sara; Gamelas,Verónica; Saraiva,Rita; Simões,Guilherme; Saiote,Joana; Ramos,JaimeAbstract Tofacitinib has emerged as a new option for ulcerative colitis. Its rapid absorption, metabolism, and clinical improvement make it an interesting option for rescue therapy in acute severe ulcerative colitis (ASUC), a situation with limited therapeutic options in patients with a long-term disease course and multiple drug failure. The management of ASUC in this setting becomes challenging, underlying the...
Primary Liver Lymphoma Presenting as Liver Nodules
Silva,João Manuel; Saraiva,Rita Ornelas; Simões,Guilherme; Araújo,Catarina; Calinas,Filipe; Coimbra,JoãoAbstract: The liver is usually affected in advanced stages of lymphoproliferative diseases, but primary liver lymphomas (PLLs) are rare. The diagnosis is usually late, especially in patients without identifiable risk factors, with consequent worse prognosis. We report the case of a 59-year-old female with progressive worsening pain in the right hypochondrium and weight loss. She was previously healthy and had a...
Comments on “Endoscopic Management of Sigmoid Volvulus in a Debilitated Populat...
Atamanalp,Sabri Selcuk; Simões,Guilherme; Rocha,Manuel Coelho da; Capela,Tiago; Silva,Mário Jorge; Ramos,Gonçalo; Coimbra,João
Cytomegalovirus Colitis Mimicking Rectal Tumour in an Undiagnosed HIV Patient
Rocha,Manuel; Borges,Verónica; Simões,Guilherme; Santos,Sara; Gamelas,Verónica; Bernardes,CarlosIntroduction: Cytomegalovirus (CMV) is the most common opportunistic agent in HIV-infected patients. It can affect the entire gastrointestinal tract, but frequently involves the oesophagus and the colon. Case Report: We report the case of a 70-year-old female, ultimately diagnosed with HIV infection, whose inaugural clinical manifestation was CMV colitis with endoscopic findings resembling a rectal tumour in wh...
Seguindo o Alfabeto... Para Diagnóstico de Hepatite Aguda E: Caso Clínico
Janeiro,Cláudia; Simões,Guilherme; Santos,Rita; Teixeira,João; Vale,Luis