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Navigating Challenges in a Case of Unusual Hepatic and Pulmonar Sarcoidosis: A ...

Gonçalves,André; Simas,Diogo; Gomes,Plácido; Leal,Carinal; Atalaia-Martins,Catarina; Vasconcelos,Helena

Abstract Introduction: Sarcoidosis, a systemic granulomatous disorder with uncertain etiology, commonly involves the lungs and, to a lesser extent, the liver. Case Presentation: A previously healthy 35-year-old Congolese female was admitted with a 7-month history of jaundice, itching, and weight loss. Despite markedly mixed hepatitis of a cholestatic pattern of liver injury, liver function tests remained normal...

Date: 2025   |   Origin: SciELO Portugal

Long-Term Abdominal Drains as a Therapeutic Option in Refractory Ascites - A Sy...

Simas,Diogo; Gonçalves,André; Caetano,Plácido Gomes Isabel; Russo,Pedro; Atalaia-Martins,Catarina; Cotrim,Isabel; Vasconcelos,Helena

Abstract Introduction: Refractory ascites (RA) is the most common complication of end-stage liver disease (ESLD) with a significant burden in terms of symptoms and overall quality of life (QoL). There are limited therapeutic options available for this population and most ultimately undergo serial large-volume paracentesis (LVP). Long-term abdominal drains (LTAD) are commonly used for malignant ascites drainage b...

Date: 2025   |   Origin: SciELO Portugal

Olmesartan-Induced Gastropathy: An Important Cause to Think about in Refractory...

Simas,Diogo; Gonçalves,André Ruge; Gomes,Plácido; Russo,Pedro; Amado,Cristina M.; Vasconcelos,Helena

Abstract Background: Angiotensin receptor blockers are a pharmacological class widely used as antihypertensive therapy. Recently, a relationship between these agents and gastrointestinal disease has been described, namely, enteropathy, gastropathy, and microscopic colitis. The mechanism is unknown, but it is thought that a cell-mediated immune reaction is involved and does not appear to be a class effect. Treat...

Date: 2025   |   Origin: SciELO Portugal

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