3 documents found, page 1 of 1
Analysis of polymorphism of the APOBEC3G gene in HIV positive patients
Gomes, Julia do Amaral; Merino, Amanda Susin; Lunge, Vagner Ricardo; Simon, DanielHuman immunodeficiency virus type 1 (HIV-1) is the etiologic agent of the current AIDS pandemic. Viral hepatitis B (HBV) and C (HCV) are highly prevalent in HIV-infected individuals. APOBEC3G (A3G) gene is a human genetic factor currently investigated in control of HIV-1 replication and progression of AIDS. Studies investigated its effect on HCV and HBV replication. APOBEC3G mediates changes that result in loss...
Genetic factors associated with fibromyalgia: a narrative review
Merino, Amanda Susin; Simon, DanielFibromyalgia is a rheumatic disorder whose main symptom is chronic generalized pain accompanied by a set of symptoms such as sleep disturbance, depression, and chronic fatigue, among others. Its pathophysiology is complex, of multifactorial origin, including the influence of genetic factors. It has been shown that individuals with fibromyalgia show a pattern of family aggregation and that the probability of an ...
The complete genome sequence of Chromobacterium violaceum reveals remarkable an...
Vasconcelos, Ana Tereza; De-Almeida, Darcy Fontoura; Hungría, Mariangela; Guimarães, Cláudia Teixeira; Antônio, Regina VasconcellosChromobacterium violaceum is one of millions of species of free-living microorganisms that populate the soil and water in the extant areas of tropical biodiversity around the world. Its complete genome sequence reveals (i) extensive alternative pathways for energy generation, (ii) ≈500 ORFs for transport-related proteins, (iii) complex and extensive systems for stress adaptation and motility, and (iv) wide-spre...