4 documents found, page 1 of 1
Metastatic cutaneous squamous cell carcinoma accounts for nearly all squamous c...
Bradley, Patrick J.; Stenman, Göran; Thompson, Lester D. R.; Skálová, Alena; Simpson, Roderick H. W.; Slootweg, Pieter J.; Franchi, AlessandroPrimary squamous cell carcinoma of the parotid gland (pSCCP) has long been recognized as a separate entity and is included in the WHO classifications of salivary gland tumors. However, it is widely accepted among head and neck pathologists that pSCCP is exceptionally rare. Yet, there are many publications describing series of pSCCP and data from SEER and other cancer register databases indicate erroneously an i...
Molecularly defined sinonasal malignancies: an overview with focus on the curre...
Skálová, Alena; Agaimy, Abbas; Bradova, Martina; Poorten, Vincent Vander; Hanna, Ehab; Guntinas-Lichius, Orlando; Franchi, Alessandro; Hellquist, HenrikClassification of tumors of the head and neck has evolved in recent decades including a widespread application of molecular testing in tumors of the sinonasal tract, salivary glands, and soft tissues with a predilection for the head and neck. The availability of new molecular techniques has allowed for the definition of multiple novel tumor types unique to head and neck sites. Moreover, an expanding spectrum of...
Development of head and neck pathology in Europe
Hellquist, Henrik; Agaimy, Abbas; Stenman, Göran; Franchi, Alessandro; Nadal, Alfons; Skalova, Alena; Leivo, Ilmo; Zidar, Nina; Simpson, Roderick H. W.This review gives a brief history of the development of head and neck pathology in Europe from a humble beginning in the 1930s to the explosive activities the last 15 years. During the decades before the introduction of immunohistochemistry in the 1980s, head and neck pathology grew as a subspeciality in many European countries. In the late 1940s, the Institute of Laryngology and Otology with its own pathology ...
High-grade transformation/dedifferentiation in salivary gland carcinomas: occur...
Skalova, Alena; Leivo, Ilmo; Hellquist, Henrik; Agaimy, Abbas; Simpson, Roderick H. W.; Stenman, Goran; Vander Poorten, Vincent; Bishop, Justin A.High-grade transformation (HGT) or dedifferentiation has been described in a variety of salivary gland carcinomas, including acinic cell carcinoma, secretory carcinoma, adenoid cystic carcinoma, epithelial-myoepithelial carcinoma, polymorphous adenocarcinoma, low-grade mucoepidermoid carcinoma, and hyalinizing clear cell carcinoma. High-grade (HG) transformed tumors are composed of a conventional low-grade comp...