6 documents found, page 1 of 1
Optimal Cutoffs for the Ratio of Arterial Oxygen Partial Pressure to Inspired O...
Pölkki, Anssi; Reinikainen, Matti; Rochwerg, Bram; Jung, Christian; Sendagire, Cornelius; Chaudhuri, Dipayan; Martin, Greg S.; Selander, TuomasPublisher Copyright: © 2025 The Author(s). Acta Anaesthesiologica Scandinavica published by John Wiley & Sons Ltd on behalf of Acta Anaesthesiologica Scandinavica Foundation.; BACKGROUND: The ratio of arterial oxygen partial pressure to fraction of inspired oxygen (PaO2/FiO2, hereafter P/F ratio) is a key component of the Sequential Organ Failure Assessment (SOFA) score. It reflects the severity of hypoxaemic r...
Rationale and Methodological Approach Underlying the Development of the Sequent...
Moreno, Rui; Rhodes, Andrew; Ranzani, Otavio; Salluh, Jorge; Berger-Estilita, Joana; Coopersmith, Craig M.; Juffermans, Nicole P.; Laffey, JohnImportance: The Sequential Organ Failure Assessment (SOFA) score was published in 1996 to describe organ dysfunction in critically ill adult patients in a readily quantifiable and sequential manner. Considerable changes have occurred over the last 3 decades in the use of organ support drugs and devices and in patient outcomes, necessitating revision of the score. Objectives: To develop definitions of organ dysf...
How to use biomarkers of infection or sepsis at the bedside
Povoa, Pedro; Coelho, Luís; Dal-Pizzol, Felipe; Ferrer, Ricard; Huttner, Angela; Conway Morris, Andrew; Nobre, Vandack; Ramirez, Paula; Rouze, AnahitaFunding This work received an unrestricted grant from GSK Portugal and was supported by Sociedade Portuguesa de Ginecologia (SPG).; Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host response to infection. In this context, biomarkers could be considered as indicators of either infection or dysregulated host response or response to treatment and/or aid clinicians to prognosti...
The Sequential Organ Failure Assessment (SOFA) Score
Moreno, Rui; Rhodes, Andrew; Piquilloud, Lise; Hernandez, Glenn; Takala, Jukka; Gershengorn, Hayley B.; Tavares, Miguel; Coopersmith, Craig M.Funding Information: RM has no competing interest to declare relevant to this article. AR has no competing interest to declare relevant to this article. LP has no competing interest to declare relevant to this article. GH has no competing interest to declare relevant to this article. JT has no competing interest to declare relevant to this article. HBG received funding from Gilead Sciences, Inc. to serve on COV...
Real-world inter-observer variability of the sequential organ failure assessmen...
Moreno, Rui; Rhodes, Andrew; Singer, Mervyn; Vincent, Jean Louis
Equilibrating SSC guidelines with individualized care
Vincent, Jean Louis; Singer, Mervyn; Einav, Sharon; Moreno, Rui; Wendon, Julia; Teboul, Jean Louis; Bakker, Jan; Hernandez, Glenn; Annane, Djillali