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Prolonged-release fampridine in multiple sclerosis: clinical data and real-worl...

Albrecht, P; Bjørnå, K; Brassat, D; Farrell, R; Feys, P; Hobart, J; Hupperts, R; Linnebank, M; Magdič, J; Oreja-Guevara, C; Pozzilli, C; Salgado, AV

Prolonged-release (PR) fampridine is the only approved medication to improve walking in multiple sclerosis (MS), having been shown to produce a clinically meaningful improvement in walking ability in the subset of MS patients with Expanded Disability Status Scale 4-7. Recent responder subgroup analyses in the phase III ENHANCE study show a large effect size in terms of an increase of 20.58 points on the patient...

Date: 2018   |   Origin: Repositório do Hospital Prof. Doutor Fernando Fonseca
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