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BDNF-Live-Exon-Visualization (BLEV) Allows Differential Detection of BDNF Trans...

Singer, Wibke; Manthey, Marie; Panford-Walsh, Rama; Matt, Lucas; Geisler, Hyun-Soon; Passeri, Eleonora; Baj, Gabriele; Tongiorgi, Enrico; Leal, Graciano

Bdnf exon-IV and exon-VI transcripts are driven by neuronal activity and are involved in pathologies related to sleep, fear or memory disorders. However, how their differential transcription translates activity changes into long-lasting network changes is elusive. Aiming to trace specifically the network controlled by exon-IV and -VI derived BDNF during activity-dependent plasticity changes, we generated a tran...

Date: 2018   |   Origin: Estudo Geral - Universidade de Coimbra
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