3 documents found, page 1 of 1
Changing human hair fibre colour and shape from the follicle
Matamá, Maria Teresa Gonçalves Macedo; Costa, Cristiana Filipa Chaves; Fernandes, Bruno; Araújo, Rita; Cruz, Célia F.; Tortosa, FranciscoIntroduction: Natural hair curvature and colour are genetically determined human traits, that we inten tionally change by applying thermal and chemical treatments to the fibre. Presently, those cosmetic methodologies act externally and their recurrent use is quite detrimental to hair fibre quality and even to our health. Objectives: This work represents a disruptive concept to modify natural hair colour and cur...
PEGylated ofloxacin nanoparticles render strong antibacterial activity against ...
Marslin, Gregory; Revina, A. M.; Khandelwal, V. K. M.; Balakumar, K.; Singh, Caroline Jeya Sheeba Daniel Sunder; Franklin, GregoryThe rise of bacterial resistance against important drugs threatens their clinical utility. Fluoroquinones, one of the most important classes of contemporary antibiotics has also reported to suffer bacterial resistance. Since the general mechanism of bacterial resistance against fluoroquinone antibiotics (e.g. ofloxacin) consists of target mutations resulting in reduced membrane permeability and increased efflux...
Signaling pathways influencing tumor microenvironment and their exploitation fo...
Singh, Caroline Jeya Sheeba Daniel Sunder; Marslin, Gregory; Mary, Revina Ann; Gregory, FranklinIn the recent years, the “tumor microenvironment” has been receiving growing attention due to its involvement in neoplastic transformation, tumor growth, invasion and protection of tumor cells from host immune response. All these events are facilitated by chemical signals produced by the tumor as well as the surrounding stromal cells. This review is divided into two main parts in which the first part discusses ...