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Tuberculosis: integrated studies for a complex disease 2050

Rezaei, Nima; Hosseini, Nastaran-Sadat; Saghazadeh, Amene; Fateh, Abolfazl; Duse, Adriano; Ahmad, Aijaz; Braley, Alexander E.; Tahta, Alican

Tuberculosis (TB) has been a disease for centuries with various challenges [1]. Like other places where challenges and opportunities come together, TB challenges were the inspiration for the scientific community to mobilize different groups for the purpose of interest. For example, with the emergence of drug resistance, there has been a huge volume of research on the discovery of new medicines and drug delivery...

Date: 2023   |   Origin: Biblioteca Digital do IPB

Structural Rigidification of N-Aryl-pyrroles into Indoles Active against Intrac...

Semenya, Dorothy; Touitou, Meir; Ribeiro, Camila Maringolo [UNESP]; Pavan, Fernando Rogerio [UNESP]; Pisano, Luca; Singh, Vinayak; Chibale, Kelly

Made available in DSpace on 2022-04-28T17:30:31Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-12-08; South African National Research Foundation-SARChI; University of London; South African Medical Research Council (SAMRC); South African Department of Science and Innovation; South African National Research Foundation; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); A series of indolyl-3-me...

Date: 2022   |   Origin: Oasisbr

Structural Rigidification of N-Aryl-pyrroles into Indoles Active against Intrac...

Semenya, Dorothy; Touitou, Meir; Ribeiro, Camila Maringolo [UNESP]; Pavan, Fernando Rogerio [UNESP]; Pisano, Luca; Singh, Vinayak; Chibale, Kelly

Made available in DSpace on 2022-04-28T18:27:38Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-01-13; South African National Research Foundation-SARChI; University of London; South African Medical Research Council (SAMRC); South African Department of Science and Innovation; South African National Research Foundation; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); A series of indolyl-3-me...

Date: 2022   |   Origin: Oasisbr

Structural Rigidification of N-Aryl-pyrroles into Indoles Active against Intrac...

Semenya, Dorothy; Touitou, Meir; Ribeiro, Camila Maringolo [UNESP]; Pavan, Fernando Rogerio [UNESP]; Pisano, Luca; Singh, Vinayak; Chibale, Kelly

Made available in DSpace on 2022-05-01T11:23:34Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-01-13; A series of indolyl-3-methyleneamines incorporating lipophilic side chains were designed through a structural rigidification approach and synthesized for investigation as new chemical entities against Mycobacterium tuberculosis (Mtb). The screening led to the identification of a 6-chloroindole analogue ...

Date: 2022   |   Origin: Oasisbr

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