Annona nutans (Annonaceae) is a plant species found in Bolivia, Paraguay, Argentina, and the Brazilian Cerrado, specifically in the states of Mato Grosso and Mato Grosso do Sul (Brazil). Its common names are Araticû-Mi and Araticû-Ñu. The research contributions regarding the chemical composition and biological activities of extracts from A. nutans are rare, with only four articles being found in the literature....
Culex quinquefasciatus (Say, 1823), known as the domestic mosquito, is a common and abundant species throughout the world, and a cosmopolitan species. The adults of this mosquito are important in terms of public and animal health since they display adaptability to different hosts. In humans, they are responsible for the transmission of various diseases. One manner of control of this vector is the use of insecti...
ABSTRACT - Duguetia furfuracea is a shrub of the Annonaceae family that occurs in several regions in Brazil. In the state of Mato Grosso do Sul this species often becomes an invading plant when the cerrado is turned into pastures. In the local folk medicine, its powdered seeds are mixed with water and used against pediculosis, and the infusion of twigs and leaves is used to treat rheumatism.. The present work l...
ABSTRACT - This study describes the chemical investigation of the ethyl acetate fraction obtained from the hydroethanolic extract of the xylopodium of Cochlospermum regium (Mart. & Schr.) Pilger, which has been associated with antimicrobial activity. Phytochemical investigation produced seven phenol derivatives: ellagic acid, gallic acid, dihydrokaempferol, dihydrokaempferol-3-O-β-glucopyranoside, dihydrokaempf...
ABSTRACT - The essential oils obtained from the dried and fresh leaves of Duguetia glabriuscula - (Annonaceae) were analyzed by GC/MS and compared. By employing the usual phytochemical workup, five aromadendrane sesquiterpenes were isolated from the essential oil obtained from fresh leaves: alloaromadendran-14b-al, alloaromadendrene, (-)-ledol, viridiflorol, and (+)-spathulenol. Alloaromadendran-14b-oic acid wa...
ABSTRACT - Memora peregrina (local name: 'ciganinha' – Bignoniaceae) is a weed that often invades pastures in the Brazilian state of Mato Grosso do Sul. From its leaves and subterranean parts, the following compounds were isolated: allantoin (20.7 w/w in subterranean parts), the iridoid 6b-hydroxyipolamiide, hyperin, 3'-O-methylhyperin, 4-hydroxy-N-methylproline, b-sitosterol, a-amirin and b-amirin, and lupeol....
Análises comparativas entre os extratos hidrometanólico de Achyrocline alata (Kunth) DC. e A. satureioides (Lam.) DC., Asteraceae,foram desenvolvidas utilizando HPLC-DAD-MS. Ambas as plantas são utilizadas indistintamente para as mesmas indicações na medicina popular de Mato Grosso do Sul, Brasil, enquanto a A. alata ("jatei-ka-há) é predominante neste estado, a A. satureioides ("marcela") é predominante nos de...
Activity - guided isolation of constituents of Unonopsis lindmanii - Annonaceae, based on the brine shrimp lethality bioassay. Extracts obtained from leaves, seeds and bark of Unonopsis lindmanii were evaluated by means of Brine Shrimp Lethality test (BSL). Through bioassay-guided chromatographic fractionation, liriodenine, an oxoaporphine alkaloid, was isolated from the bark extracts as the bioactive compound....
The sesquiterpene (+)-allo-aromadendrane-10β-14-diol 1 was the lead compound to the preparation of several derivatives in order to test their biological activity against A. salina, C. sphaerospermum, E. coli and S. aureus. In this way the monoalcohols (+)-viridiflorol 4, 9 and 11 were synthesized from 1 together with the acetal 6, the ketal 7, and the ketone 8. The oxirane 3 and nitrile 5 were also prepared usi...
Five novel santalane-type sesquiterpenes were isolated from the stem bark of Duguetia glabriuscula – Annonaceae. Their structures have been established on the basis of spectral data and chemical evidences (1H and 13C NMR, HMQC, HMBC) as (+)-a-santal-10-en-9-ol (1), (+)-a-santalan-10,11-epoxy-9-ol (2), a-santal-11-en-9,10-diol (3), (+)-a-santalan-9,10,11-triol (4), and (+)-a-santalan-9,11-epoxy-10-ol (5). Polyca...